Syndax Pharmaceuticals (SNDX) Return on Equity [ROE] (2016 - 2026)
Syndax Pharmaceuticals (SNDX) recorded Return on Equity [ROE] of -625.06% in Q2 2026, down 456.85 percentage points from -168.21% a year earlier and down 240.26 percentage points from the prior quarter.
Powered by 
Analysis
Syndax Pharmaceuticals (SNDX) Return on Equity [ROE] (2016 - 2026) Analysis & Trends
For FY2025, Syndax Pharmaceuticals reported Return on Equity [ROE] of -141.95%, down 67.49 percentage points from FY2024.
- Annual Return on Equity [ROE] has declined for four straight years, with a five-year change of -90.54 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -74.46% in FY2024 (-33.54 pp), -40.91% in FY2023 (-6.88 pp), -34.03% in FY2022 (-41.52 pp) and 7.49% in FY2021 (+58.89 pp).
- The Q2 2026 figure is the lowest quarterly Return on Equity [ROE] in data going back to Q2 2016.
- On a year-over-year basis, Return on Equity [ROE] has declined for 15 consecutive quarters, with an average year-over-year change of -162.39 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 46.11 percentage points in Q4 2021, against a drop of 456.85 percentage points in Q2 2026 at the low end.
- Per Business Quant, the preceding three quarters came in at -384.79% (Q1 2026), -278.09% (Q4 2025) and -206.17% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 82.09% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 25.32% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | - |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 7.21% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 84.40% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 21.39% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 83.75% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -18.38% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 4.97% |
| 10 | Syndax Pharmaceuticals | 1.57 Bn | -160.92 Mn | 69.58 Mn | -625.06% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -625.06% |
| Mar 31, 2026 | -384.79% |
| Dec 31, 2025 | -278.09% |
| Sep 30, 2025 | -206.17% |
| Jun 30, 2025 | -168.21% |
| Mar 31, 2025 | -126.33% |
| Dec 31, 2024 | -95.81% |
| Sep 30, 2024 | -74.15% |
| Jun 30, 2024 | -56.96% |
| Mar 31, 2024 | -45.95% |
| Dec 31, 2023 | -45.76% |
| Sep 30, 2023 | -46.28% |
| Jun 30, 2023 | -38.23% |
| Mar 31, 2023 | -33.83% |
| Dec 31, 2022 | -37.00% |
| Sep 30, 2022 | -4.02% |
| Jun 30, 2022 | 0.11% |
| Mar 31, 2022 | 3.86% |
| Dec 31, 2021 | 8.14% |
| Sep 30, 2021 | -44.26% |
API Access
Syndax Pharmaceuticals Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SNDX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SNDX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SNDX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();