Shuttle Pharmaceuticals Holdings (SHPH) Return on Capital Employed (2022 - 2026)

Shuttle Pharmaceuticals Holdings (SHPH) recorded quarterly Return on Capital Employed of 394.16% in Q1 2026, down 131.67% quarter-over-quarter from 1244.66% in Q4 2025, and up 4151.0% on a YoY basis from 9.27% in Q1 2025.

Shuttle Pharmaceuticals Holdings (SHPH) Return on Capital Employed (2022 - 2026) Analysis & Trends

Shuttle Pharmaceuticals Holdings' Return on Capital Employed history runs 5 years deep, the most recent figure standing at 394.16% for Q1 2026.

  • In Q1 2026, Return on Capital Employed rose 4151.0% year-over-year to 394.16%; the TTM figure through Mar 2026 stood at 394.16% (up 4151.0% YoY), while the FY2025 annual figure was 807.51%, up 109305.0% from the prior year.
  • Return on Capital Employed was 394.16% for Q1 2026 at Shuttle Pharmaceuticals Holdings, down from 1244.66% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 1244.66% in Q4 2025 to a low of 13704.01% in Q4 2024.
  • Historically, Return on Capital Employed has averaged 1662.76% across 5 years, with a median of 194.02% in 2024.
  • The sharpest annual moves came in 2024 and 2025: Return on Capital Employed slumped 1359919 bps in 2024, then soared 1494866 bps in 2025.
  • A 5-year view of Return on Capital Employed shows it stood at 29.14% in 2022, then slumped by 260 bps to 104.82% in 2023, then slumped by 12974 bps to 13704.01% in 2024, then soared by 109 bps to 1244.66% in 2025, then sank by 132 bps to 394.16% in 2026.
  • The last three Return on Capital Employed figures came in at 394.16% (Q1 2026), 1244.66% (Q4 2025), and 426.21% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Teva Pharmaceutical Industries 38.34 Bn 34.60 Bn 1.97 Bn 8.52%
2 Zoetis 33.27 Bn 31.33 Bn 1.62 Bn 27.58%
3 United Therapeutics 23.75 Bn 21.60 Bn 648.10 Mn 21.43%
4 Aurora Cannabis 17.11 Bn 17.03 Bn 33.43 Mn -
5 Neurocrine Biosciences 16.37 Bn 15.05 Bn 800.70 Mn 20.04%
6 Elanco Animal Health 11.78 Bn 11.35 Bn 785.00 Mn 7.34%
7 Alkermes 7.05 Bn 6.54 Bn -116.06 Mn 6.92%
8 Lantheus Holdings 6.49 Bn 5.99 Bn 230.92 Mn 14.85%
9 Hims & Hers Health 6.19 Bn 5.44 Bn 396.79 Mn -1.92%
10 Shuttle Pharmaceuticals Holdings 2.32 Mn 1.26 Mn - -394.16%

Historic Data

Download Data
DateValue
Mar 31, 2026 -394.16%
Dec 31, 2025 1,244.66%
Sep 30, 2025 -426.21%
Jun 30, 2025 -314.72%
Mar 31, 2025 -435.67%
Dec 31, 2024 -13,704.01%
Sep 30, 2024 -8,568.55%
Jun 30, 2024 -239.68%
Mar 31, 2024 -148.37%
Dec 31, 2023 -104.82%
Sep 30, 2023 -70.45%
Jun 30, 2023 -47.71%
Mar 31, 2023 -39.85%
Dec 31, 2022 -29.14%