Sera Prognostics (SERA) Return on Equity [ROE] (2021 - 2026)
Sera Prognostics (SERA) reported Return on Equity [ROE] of -52.61% for Q2 2026, down 16.17 percentage points from -36.45% a year earlier and down 7.38 percentage points from the prior quarter.
Sera Prognostics (SERA) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, Sera Prognostics posted Return on Equity [ROE] of -52.37%, up 5.14 percentage points from FY2024.
- Return on Equity [ROE] has a four-year change of +503.91 percentage points (FY2021 to FY2025).
- By year, Return on Equity [ROE] came in at -57.50% in FY2024 (-12.28 pp), -45.22% in FY2023 (-6.73 pp), -38.49% in FY2022 (+517.78 pp) and -556.27% in FY2021.
- The Q2 2026 figure ranks as the lowest quarterly Return on Equity [ROE] since Q4 2024.
- Year over year, Return on Equity [ROE] gained in five of the last eight quarters, with an average year-over-year change of +4.30 percentage points.
- The high point for year-over-year Return on Equity [ROE] in five years was Q3 2022 (a gain of 363.00 percentage points); the low point was Q4 2022 (a drop of 19.33 percentage points).
- Per Business Quant data, the three quarters before Q2 2026 came in at -45.24% (Q1 2026), -40.94% (Q4 2025) and -38.84% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 93.06 Bn | 92.50 Bn | - | - |
| 2 | Natera | 59.36 Bn | 55.04 Bn | 485.19 Mn | -10.70% |
| 3 | Quest Diagnostics | 25.72 Bn | 24.15 Bn | 1.03 Bn | 14.38% |
| 4 | Labcorp Holdings | 24.93 Bn | 22.69 Bn | 1.11 Bn | 11.58% |
| 5 | Guardant Health | 23.83 Bn | 19.89 Bn | 219.03 Mn | - |
| 6 | Tenet Healthcare | 20.58 Bn | 11.72 Bn | - | 47.84% |
| 7 | Tempus AI | 14.35 Bn | 11.38 Bn | 246.50 Mn | -57.32% |
| 8 | Encompass Health | 11.99 Bn | 12.46 Bn | - | 24.83% |
| 9 | BrightSpring Health Services | 11.21 Bn | 9.55 Bn | 492.75 Mn | 18.16% |
| 10 | Sera Prognostics | 105.50 Mn | 105.50 Mn | -20,000.00 | -52.61% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -52.61% |
| Mar 31, 2026 | -45.24% |
| Dec 31, 2025 | -40.94% |
| Sep 30, 2025 | -38.84% |
| Jun 30, 2025 | -36.45% |
| Mar 31, 2025 | -47.43% |
| Dec 31, 2024 | -66.21% |
| Sep 30, 2024 | -58.47% |
| Jun 30, 2024 | -53.07% |
| Mar 31, 2024 | -53.25% |
| Dec 31, 2023 | -53.35% |
| Sep 30, 2023 | -52.35% |
| Jun 30, 2023 | -51.90% |
| Mar 31, 2023 | -47.32% |
| Dec 31, 2022 | -44.36% |
| Sep 30, 2022 | -42.69% |
| Jun 30, 2022 | -38.10% |
| Mar 31, 2022 | -31.68% |
| Dec 31, 2021 | -25.03% |
| Sep 30, 2021 | -405.69% |
Sera Prognostics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SERA&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "SERA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=SERA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();