Septerna (SEPN) Return on Sales (2023 - 2026)
Septerna's quarterly Return on Sales came in at 0.0% in Q1 2026, up 98.0% year-on-year from 0.0% in Q1 2025, and up 26.8% quarter-over-quarter from 0.0% in Q4 2025.
Septerna has reported Return on Sales for 4 years, with the latest figure at 0.0% in Q1 2026.
- For the quarter ending Q1 2026, Return on Sales rose 98.0% year-over-year to 0.0%; the trailing twelve-month figure through Mar 2026 stood at 0.0% (up 81.0% YoY), and the FY2025 full-year result was 0.01%, up 66.0% from the prior year.
- Return on Sales for Q1 2026 stood at 0.0%, up from 0.0% in the prior quarter.
- The five-year high for Return on Sales was 0.0% in Q3 2025, with the low at 3.32% in Q3 2023.
- Average Return on Sales over 4 years is 1.0%, with a median of 0.97% recorded in 2024.
- Year-over-year, Return on Sales surged 215 bps in 2024 and tumbled 164 bps in 2025.
- Tracing SEPN's Return on Sales over 4 years: stood at 1.54% in 2023, then surged by 37 bps to 0.97% in 2024, then soared by 100 bps to 0.0% in 2025, then gained by 27 bps to 0.0% in 2026.
- The last three Return on Sales figures came in at 0.0% (Q1 2026), 0.0% (Q4 2025), and 0.0% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.00% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 0.00% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | 0.00% |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 0.00% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 0.00% |
| 10 | Septerna | 1.34 Bn | 1.34 Bn | - | 0.00% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 0.00% |
| Dec 31, 2025 | 0.00% |
| Sep 30, 2025 | 0.00% |
| Jun 30, 2025 | -2.09% |
| Mar 31, 2025 | -0.98% |
| Dec 31, 2024 | -0.97% |
| Sep 30, 2024 | -1.17% |
| Jun 30, 2024 | -0.45% |
| Mar 31, 2024 | -0.45% |
| Dec 31, 2023 | -1.54% |
| Sep 30, 2023 | -3.32% |