Septerna (SEPN) Return on Sales (2023 - 2026)

Septerna's Return on Sales history runs 4 years deep, the most recent figure standing at 0.0% for Q1 2026.

• On a quarterly basis, Return on Sales rose 98.0% year-over-year to 0.0% in Q1 2026; TTM through Mar 2026 was 0.0%, a 81.0% increase from a year earlier, with the FY2025 full-year figure at 0.01%, up 66.0% from the prior year.
• Return on Sales advanced to 0.0% in Q1 2026 per SEPN's latest filing, from 0.0% in the prior quarter.
• Across five years, Return on Sales topped out at 0.0% in Q3 2025 and bottomed at 3.32% in Q3 2023.
• The 4-year median for Return on Sales is 0.97% (2024), against an average of 1.0%.
• Across the five-year window, Return on Sales surged 215 bps in 2024 and tumbled 164 bps in 2025, its largest moves.
• Year by year, Return on Sales stood at 1.54% in 2023, then jumped by 37 bps to 0.97% in 2024, then surged by 100 bps to 0.0% in 2025, then rose by 27 bps to 0.0% in 2026.
• Per Business Quant, the three latest SEPN Return on Sales figures stand at 0.0% (Q1 2026), 0.0% (Q4 2025), and 0.0% (Q3 2025).