Septerna (SEPN) Return on Sales (2023 - 2025)

Septerna (SEPN) has 3 years of Return on Sales data on record, last reported at 1.96% in Q4 2025.

  • For Q4 2025, Return on Sales rose 9944.0% year-over-year to 1.96%; the TTM value through Dec 2025 reached 0.2%, up 6736.0%, while the annual FY2025 figure was 0.2%, 6699.0% up from the prior year.
  • Return on Sales reached 1.96% in Q4 2025 per SEPN's latest filing, up from 0.38% in the prior quarter.
  • Across five years, Return on Sales topped out at 1.96% in Q4 2025 and bottomed at 331.67% in Q3 2023.
  • Average Return on Sales over 3 years is 104.5%, with a median of 97.48% recorded in 2024.
  • Peak YoY movement for Return on Sales: soared 21506bps in 2024, then crashed -16370bps in 2025.
  • A 3-year view of Return on Sales shows it stood at 331.67% in 2023, then soared by 71bps to 97.48% in 2024, then soared by 102bps to 1.96% in 2025.
  • Per Business Quant database, its latest 3 readings for Return on Sales were 1.96% in Q4 2025, 0.38% in Q3 2025, and 208.72% in Q2 2025.