Septerna (SEPN) Return on Sales: 2024-2025

Historic Return on Sales for Septerna (SEPN) over the last 2 years, with Sep 2025 value amounting to -2.67%.

  • Septerna's Return on Sales rose 1359.00% to -2.67% in Q3 2025 from the same period last year, while for Sep 2025 it was -2.67%, marking a year-over-year increase of 1359.00%. This contributed to the annual value of -66.79% for FY2024, which is 9441.00% down from last year.
  • As of Q3 2025, Septerna's Return on Sales stood at -2.67%, which was up 97.79% from -120.53% recorded in Q2 2025.
  • Septerna's Return on Sales' 5-year high stood at -2.67% during Q3 2025, with a 5-year trough of -120.53% in Q2 2025.
  • Its 2-year average for Return on Sales is -49.23%, with a median of -41.71% in 2024.
  • Within the past 5 years, the most significant YoY rise in Septerna's Return on Sales was 1,359bps (2025), while the steepest drop was 11,292bps (2025).
  • Over the past 2 years, Septerna's Return on Sales (Quarterly) stood at -67.16% in 2024, then spiked by 1,359bps to -2.67% in 2025.
  • Its last three reported values are -2.67% in Q3 2025, -120.53% for Q2 2025, and -81.19% during Q1 2025.