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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Septerna (SEPN) Return on Sales (2023 - 2025)

Septerna has reported Return on Sales over the past 3 years, most recently at 0.45% for Q4 2025.

  • Quarterly results put Return on Sales at 0.45% for Q4 2025, up 9936.0% from a year ago — trailing twelve months through Dec 2025 was 1.06% (up 6656.0% YoY), and the annual figure for FY2025 was 1.06%, up 6618.0%.
  • Return on Sales for Q4 2025 was 0.45% at Septerna, down from 0.38% in the prior quarter.
  • Over the last five years, Return on Sales for SEPN hit a ceiling of 0.38% in Q3 2025 and a floor of 331.67% in Q3 2023.
  • Median Return on Sales over the past 3 years was 98.94% (2024), compared with a mean of 109.91%.
  • Biggest five-year swings in Return on Sales: surged 21506bps in 2024 and later tumbled -16370bps in 2025.
  • Septerna's Return on Sales stood at 153.84% in 2023, then soared by 35bps to 99.81% in 2024, then skyrocketed by 100bps to 0.45% in 2025.
  • The last three reported values for Return on Sales were 0.45% (Q4 2025), 0.38% (Q3 2025), and 208.72% (Q2 2025) per Business Quant data.