Septerna (SEPN) Return on Equity: 2024-2025

Historic Return on Equity for Septerna (SEPN) over the last 2 years, with Sep 2025 value amounting to -0.15%.

  • Septerna's Return on Equity fell 36.00% to -0.15% in Q3 2025 from the same period last year, while for Sep 2025 it was -0.15%, marking a year-over-year decrease of 36.00%. This contributed to the annual value of -0.38% for FY2024, which is N/A change from last year.
  • As of Q3 2025, Septerna's Return on Equity stood at -0.15%, which was up 31.78% from -0.22% recorded in Q2 2025.
  • In the past 5 years, Septerna's Return on Equity registered a high of 0.21% during Q3 2024, and its lowest value of -0.43% during Q4 2024.
  • For the 2-year period, Septerna's Return on Equity averaged around -0.12%, with its median value being -0.17% (2025).
  • Data for Septerna's Return on Equity shows a maximum YoY plummeted of 36bps (in 2025) over the last 5 years.
  • Over the past 2 years, Septerna's Return on Equity (Quarterly) stood at -0.43% in 2024, then tumbled by 36bps to -0.15% in 2025.
  • Its Return on Equity stands at -0.15% for Q3 2025, versus -0.22% for Q2 2025 and -0.19% for Q1 2025.