Schrodinger (SDGR) Operating Margin (2019 - 2026)
Schrodinger (SDGR) recorded quarterly Operating Margin of 83.28% in Q1 2026, down 323.46% quarter-over-quarter from 19.67% in Q4 2025, and up 217.0% on a YoY basis from 26.27% in Q1 2025.
Schrodinger (SDGR) Operating Margin (2019 - 2026) Analysis & Trends
Schrodinger's Operating Margin history runs 8 years deep, the most recent figure standing at 83.28% for Q1 2026.
- In Q1 2026, Operating Margin rose 217.0% year-over-year to 83.28%; the TTM figure through Mar 2026 stood at 64.65% (up 1897.0% YoY), while the FY2025 annual figure was 65.23%, up 3562.0% from the prior year.
- Operating Margin was 83.28% for Q1 2026 at Schrodinger, down from 19.67% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 19.67% in Q4 2025 to a low of 193.88% in Q3 2024.
- Historically, Operating Margin has averaged 95.43% across 5 years, with a median of 85.45% in 2025.
- The sharpest annual moves came in 2024 and 2025: Operating Margin sank 13717 bps in 2024, then jumped 10931 bps in 2025.
- A 5-year view of Operating Margin shows it stood at 50.2% in 2022, then rose by 20 bps to 39.96% in 2023, then jumped by 41 bps to 23.45% in 2024, then increased by 16 bps to 19.67% in 2025, then tumbled by 323 bps to 83.28% in 2026.
- The last three Operating Margin figures came in at 83.28% (Q1 2026), 19.67% (Q4 2025), and 84.58% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Veeva Systems | 27.35 Bn | 20.79 Bn | 662.02 Mn | 30.93% |
| 2 | BrightSpring Health Services | 12.12 Bn | 11.24 Bn | 482.22 Mn | 3.36% |
| 3 | Healthequity | 7.42 Bn | 7.15 Bn | 256.31 Mn | 29.03% |
| 4 | Hinge Health | 4.95 Bn | 4.64 Bn | 154.23 Mn | 17.59% |
| 5 | Doximity | 3.80 Bn | 3.05 Bn | 125.97 Mn | 17.08% |
| 6 | 10x Genomics | 3.78 Bn | 3.24 Bn | 106.18 Mn | -11.30% |
| 7 | Waystar Holding | 3.65 Bn | 3.49 Bn | 268.04 Mn | 25.64% |
| 8 | Privia Health | 2.66 Bn | 2.29 Bn | 595.71 Mn | 1.23% |
| 9 | Omnicell | 1.90 Bn | 1.73 Bn | 140.36 Mn | 5.44% |
| 10 | Schrodinger | 1.06 Bn | 659.83 Mn | 29.55 Mn | -83.28% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -83.28% |
| Dec 31, 2025 | -19.67% |
| Sep 30, 2025 | -84.58% |
| Jun 30, 2025 | -96.61% |
| Mar 31, 2025 | -85.45% |
| Dec 31, 2024 | -23.45% |
| Sep 30, 2024 | -193.88% |
| Jun 30, 2024 | -111.40% |
| Mar 31, 2024 | -184.25% |
| Dec 31, 2023 | -39.96% |
| Sep 30, 2023 | -132.00% |
| Jun 30, 2023 | -173.73% |
| Mar 31, 2023 | -47.08% |
| Dec 31, 2022 | -50.20% |
| Sep 30, 2022 | -124.83% |
| Jun 30, 2022 | -113.01% |
| Mar 31, 2022 | -58.86% |
| Dec 31, 2021 | -48.77% |
| Sep 30, 2021 | -116.16% |
| Jun 30, 2021 | -101.87% |