Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026)
Rhythm Pharmaceuticals (RYTM) posted Net Margin of -70.68% for Q2 2026, up 28.25 percentage points from -98.93% a year earlier and up 23.72 percentage points from the prior quarter.
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Analysis
Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Net Margin at Rhythm Pharmaceuticals was -87.62%, up 32.93 percentage points year-over-year; for FY2025, it was -106.41%, up 96.91 percentage points from FY2024.
- Annual Net Margin has increased for four consecutive years, with a four-year change of +2100.69 percentage points (FY2021 to FY2025).
- In prior years, Rhythm Pharmaceuticals' Net Margin was -203.32% in FY2024 (+35.20 pp), -238.52% in FY2023 (+527.70 pp), -766.22% in FY2022 (+1440.88 pp) and -2207.10% in FY2021.
- The Q2 2026 figure stands as the highest quarterly Net Margin since Q1 2021.
- On a year-over-year basis, Net Margin has increased in each of the last nine quarters, with an average year-over-year change of +83.96 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Net Margin in the past five years was Q2 2022, with a gain of 12419.32 percentage points; the weakest was Q1 2022, with a drop of 128522.30 percentage points.
- According to Business Quant data, Net Margin for the three prior quarters was -94.40% (Q1 2026), -85.30% (Q4 2025) and -105.81% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Rhythm Pharmaceuticals | 6.78 Bn | 5.65 Bn | 62.32 Mn | -70.68% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -70.68% |
| Mar 31, 2026 | -94.40% |
| Dec 31, 2025 | -85.30% |
| Sep 30, 2025 | -105.81% |
| Jun 30, 2025 | -98.93% |
| Mar 31, 2025 | -155.39% |
| Dec 31, 2024 | -106.70% |
| Sep 30, 2024 | -135.24% |
| Jun 30, 2024 | -115.42% |
| Mar 31, 2024 | -544.43% |
| Dec 31, 2023 | -171.80% |
| Sep 30, 2023 | -196.25% |
| Jun 30, 2023 | -242.98% |
| Mar 31, 2023 | -454.96% |
| Dec 31, 2022 | -483.42% |
| Sep 30, 2022 | -953.80% |
| Jun 30, 2022 | -496.37% |
| Mar 31, 2022 | -3,522.30% |
| Dec 31, 2021 | -2,359.16% |
| Sep 30, 2021 | -3,415.08% |
API Access
Rhythm Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=RYTM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "RYTM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=RYTM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();