Replimune (REPL) Profit After Tax (2017 - 2025)

Replimune's (REPL) quarterly Profit After Tax came in at -$70.9 million in Q4 2025, down 6.94% year-on-year from -$76.2 million in Q4 2024, and up 14.68% quarter-over-quarter from -$83.1 million in Q3 2025.

Replimune (REPL) Profit After Tax (2017 - 2025) Analysis & Trends

Replimune has disclosed Profit After Tax across 9 years of filings, most recently posting -$70.9 million for Q4 2025.

  • Profit After Tax for Q4 2025 came in at -$70.9 million, down 6.94% year-over-year; the trailing twelve-month figure through Dec 2025 was -$314.8 million (down 38.18% YoY), and the FY2025 annual result was -$247.3 million, down 14.82% from the prior year.
  • Profit After Tax came in at -$70.9 million for Q4 2025 at Replimune, up from -$83.1 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of -$21.5 million in Q1 2021 to a low of -$86.7 million in Q2 2025.
  • The 5-year median for Profit After Tax is -$50.3 million (2023), against an average of -$50.8 million.
  • Across the five-year window, Profit After Tax advanced 11.64% in 2024 and tumbled 61.22% in 2025, its largest moves.
  • Replimune's Profit After Tax stood at -$29.7 million in 2021, then plunged by 33.75% to -$39.7 million in 2022, then dropped by 28.8% to -$51.1 million in 2023, then declined by 29.69% to -$66.3 million in 2024, then slipped by 6.94% to -$70.9 million in 2025.
  • The last three Profit After Tax figures came in at -$70.9 million (Q4 2025), -$83.1 million (Q3 2025), and -$86.7 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -2.97 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 30.90 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -14.46 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.63 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -753,254.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.03 Bn
9 Abivax 91.71 Bn 91.71 Bn - -56.74 Mn
10 Replimune 780.01 Mn 510.88 Mn - -70.90 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -70.90 Mn
Sep 30, 2025 -83.10 Mn
Jun 30, 2025 -86.69 Mn
Mar 31, 2025 -74.10 Mn
Dec 31, 2024 -66.30 Mn
Sep 30, 2024 -53.06 Mn
Jun 30, 2024 -53.77 Mn
Mar 31, 2024 -54.69 Mn
Dec 31, 2023 -51.12 Mn
Sep 30, 2023 -60.04 Mn
Jun 30, 2023 -49.56 Mn
Mar 31, 2023 -49.00 Mn
Dec 31, 2022 -39.69 Mn
Sep 30, 2022 -43.10 Mn
Jun 30, 2022 -42.25 Mn
Mar 31, 2022 -31.70 Mn
Dec 31, 2021 -29.67 Mn
Sep 30, 2021 -29.36 Mn
Jun 30, 2021 -27.31 Mn
Mar 31, 2021 -21.50 Mn