Replimune (REPL) Net Income (2017 - 2025)

Replimune's (REPL) quarterly Net Income came in at -$70.9 million in Q4 2025, down 6.92% year-on-year from -$76.2 million in Q4 2024, and up 13.59% quarter-over-quarter from -$82.1 million in Q3 2025.

Replimune (REPL) Net Income (2017 - 2025) Analysis & Trends

Replimune has disclosed Net Income across 9 years of filings, most recently posting -$70.9 million for Q4 2025.

  • Net Income for Q4 2025 came in at -$70.9 million, down 6.92% year-over-year; the trailing twelve-month figure through Dec 2025 was -$314.3 million (down 37.72% YoY), and the FY2025 annual result was -$247.3 million, down 14.61% from the prior year.
  • Net Income came in at -$70.9 million for Q4 2025 at Replimune, up from -$82.1 million in the prior quarter.
  • In the past five years, Net Income ranged from a high of -$22.1 million in Q1 2021 to a low of -$87.2 million in Q2 2025.
  • The 5-year median for Net Income is -$50.3 million (2023), against an average of -$50.9 million.
  • Across the five-year window, Net Income advanced 11.64% in 2024 and plunged 62.13% in 2025, its largest moves.
  • Replimune's Net Income stood at -$29.6 million in 2021, then tumbled by 34.04% to -$39.7 million in 2022, then dropped by 28.8% to -$51.1 million in 2023, then slipped by 29.77% to -$66.3 million in 2024, then retreated by 6.92% to -$70.9 million in 2025.
  • The last three Net Income figures came in at -$70.9 million (Q4 2025), -$82.1 million (Q3 2025), and -$87.2 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -2.97 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 30.80 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -14.46 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.40 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -1.50 Mn
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.03 Bn
9 Abivax 91.71 Bn 91.71 Bn - -56.48 Mn
10 Replimune 780.01 Mn 510.88 Mn - -70.93 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -70.93 Mn
Sep 30, 2025 -82.08 Mn
Jun 30, 2025 -87.18 Mn
Mar 31, 2025 -74.14 Mn
Dec 31, 2024 -66.34 Mn
Sep 30, 2024 -53.06 Mn
Jun 30, 2024 -53.77 Mn
Mar 31, 2024 -55.08 Mn
Dec 31, 2023 -51.12 Mn
Sep 30, 2023 -60.04 Mn
Jun 30, 2023 -49.56 Mn
Mar 31, 2023 -49.24 Mn
Dec 31, 2022 -39.69 Mn
Sep 30, 2022 -43.10 Mn
Jun 30, 2022 -42.25 Mn
Mar 31, 2022 -31.86 Mn
Dec 31, 2021 -29.61 Mn
Sep 30, 2021 -29.17 Mn
Jun 30, 2021 -27.29 Mn
Mar 31, 2021 -22.09 Mn