Replimune (REPL) Invested Capital (2018 - 2025)

Replimune's (REPL) quarterly Invested Capital came in at $235.5 million in Q4 2025, down 53.64% year-on-year from $508.1 million in Q4 2024, and down 18.37% quarter-over-quarter from $288.5 million in Q3 2025.

Replimune (REPL) Invested Capital (2018 - 2025) Analysis & Trends

Replimune has disclosed Invested Capital across 8 years of filings, most recently posting $235.5 million for Q4 2025.

  • Invested Capital for Q4 2025 came in at $235.5 million, down 53.64% year-over-year; the trailing twelve-month figure through Dec 2025 was $235.5 million (down 53.64% YoY), and the FY2025 annual result was $462.2 million, up 10.23% from the prior year.
  • Invested Capital came in at $235.5 million for Q4 2025 at Replimune, down from $288.5 million in the prior quarter.
  • In the past five years, Invested Capital ranged from a high of $622.0 million in Q4 2022 to a low of $235.5 million in Q4 2025.
  • The 5-year median for Invested Capital is $457.3 million (2024), against an average of $451.7 million.
  • Across the five-year window, Invested Capital jumped 157.72% in 2021 and plunged 53.64% in 2025, its largest moves.
  • Replimune's Invested Capital stood at $464.6 million in 2021, then surged by 33.9% to $622.0 million in 2022, then slipped by 28.01% to $447.8 million in 2023, then advanced by 13.46% to $508.1 million in 2024, then slumped by 53.64% to $235.5 million in 2025.
  • The last three Invested Capital figures came in at $235.5 million (Q4 2025), $288.5 million (Q3 2025), and $362.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 7.14 Bn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 795.79 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 595,226.00
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn 1.00 Bn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 14.38 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 19.36 Bn
9 Abivax 91.71 Bn 91.71 Bn - 502.95 Mn
10 Replimune 780.01 Mn 510.88 Mn - 235.53 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 235.53 Mn
Sep 30, 2025 288.52 Mn
Jun 30, 2025 362.08 Mn
Mar 31, 2025 462.22 Mn
Dec 31, 2024 508.07 Mn
Sep 30, 2024 407.31 Mn
Jun 30, 2024 452.45 Mn
Mar 31, 2024 419.32 Mn
Dec 31, 2023 447.80 Mn
Sep 30, 2023 491.56 Mn
Jun 30, 2023 540.53 Mn
Mar 31, 2023 583.94 Mn
Dec 31, 2022 622.05 Mn
Sep 30, 2022 410.88 Mn
Jun 30, 2022 437.15 Mn
Mar 31, 2022 411.23 Mn
Dec 31, 2021 464.55 Mn
Sep 30, 2021 484.53 Mn
Jun 30, 2021 506.20 Mn
Mar 31, 2021 498.73 Mn