Replimune (REPL) Invested Capital (2018 - 2025)
Replimune's (REPL) quarterly Invested Capital came in at $235.5 million in Q4 2025, down 53.64% year-on-year from $508.1 million in Q4 2024, and down 18.37% quarter-over-quarter from $288.5 million in Q3 2025.
Replimune (REPL) Invested Capital (2018 - 2025) Analysis & Trends
Replimune has disclosed Invested Capital across 8 years of filings, most recently posting $235.5 million for Q4 2025.
- Invested Capital for Q4 2025 came in at $235.5 million, down 53.64% year-over-year; the trailing twelve-month figure through Dec 2025 was $235.5 million (down 53.64% YoY), and the FY2025 annual result was $462.2 million, up 10.23% from the prior year.
- Invested Capital came in at $235.5 million for Q4 2025 at Replimune, down from $288.5 million in the prior quarter.
- In the past five years, Invested Capital ranged from a high of $622.0 million in Q4 2022 to a low of $235.5 million in Q4 2025.
- The 5-year median for Invested Capital is $457.3 million (2024), against an average of $451.7 million.
- Across the five-year window, Invested Capital jumped 157.72% in 2021 and plunged 53.64% in 2025, its largest moves.
- Replimune's Invested Capital stood at $464.6 million in 2021, then surged by 33.9% to $622.0 million in 2022, then slipped by 28.01% to $447.8 million in 2023, then advanced by 13.46% to $508.1 million in 2024, then slumped by 53.64% to $235.5 million in 2025.
- The last three Invested Capital figures came in at $235.5 million (Q4 2025), $288.5 million (Q3 2025), and $362.1 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Invested Cap. (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | 7.14 Bn |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | 795.79 Mn |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | 595,226.00 |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | 1.00 Bn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | 14.38 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 19.36 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | 502.95 Mn |
| 10 | Replimune | 780.01 Mn | 510.88 Mn | - | 235.53 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 235.53 Mn |
| Sep 30, 2025 | 288.52 Mn |
| Jun 30, 2025 | 362.08 Mn |
| Mar 31, 2025 | 462.22 Mn |
| Dec 31, 2024 | 508.07 Mn |
| Sep 30, 2024 | 407.31 Mn |
| Jun 30, 2024 | 452.45 Mn |
| Mar 31, 2024 | 419.32 Mn |
| Dec 31, 2023 | 447.80 Mn |
| Sep 30, 2023 | 491.56 Mn |
| Jun 30, 2023 | 540.53 Mn |
| Mar 31, 2023 | 583.94 Mn |
| Dec 31, 2022 | 622.05 Mn |
| Sep 30, 2022 | 410.88 Mn |
| Jun 30, 2022 | 437.15 Mn |
| Mar 31, 2022 | 411.23 Mn |
| Dec 31, 2021 | 464.55 Mn |
| Sep 30, 2021 | 484.53 Mn |
| Jun 30, 2021 | 506.20 Mn |
| Mar 31, 2021 | 498.73 Mn |