Replimune (REPL) EBT (2017 - 2025)
Replimune's (REPL) quarterly EBT came in at -$71.2 million in Q4 2025, down 8.33% year-on-year from -$77.7 million in Q4 2024, and up 13.21% quarter-over-quarter from -$82.1 million in Q3 2025.
Replimune (REPL) EBT (2017 - 2025) Analysis & Trends
Replimune has disclosed EBT across 9 years of filings, most recently posting -$71.2 million for Q4 2025.
- EBT for Q4 2025 came in at -$71.2 million, down 8.33% year-over-year; the trailing twelve-month figure through Dec 2025 was -$314.7 million (down 38.21% YoY), and the FY2025 annual result was -$246.8 million, down 14.6% from the prior year.
- EBT came in at -$71.2 million for Q4 2025 at Replimune, up from -$82.1 million in the prior quarter.
- In the past five years, EBT ranged from a high of -$22.1 million in Q1 2021 to a low of -$87.2 million in Q2 2025.
- The 5-year median for EBT is -$50.0 million (2023), against an average of -$50.8 million.
- Across the five-year window, EBT gained 11.93% in 2024 and plunged 62.13% in 2025, its largest moves.
- Replimune's EBT stood at -$29.6 million in 2021, then tumbled by 34.04% to -$39.7 million in 2022, then fell by 27.61% to -$50.6 million in 2023, then declined by 29.85% to -$65.8 million in 2024, then declined by 8.33% to -$71.2 million in 2025.
- The last three EBT figures came in at -$71.2 million (Q4 2025), -$82.1 million (Q3 2025), and -$87.2 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | -26.94 Mn |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | 19.60 Mn |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | -15.31 Mn |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | -3.18 Mn |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | -1.50 Mn |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 1.25 Bn |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | -56.48 Mn |
| 10 | Replimune | 780.01 Mn | 510.88 Mn | - | -71.24 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -71.24 Mn |
| Sep 30, 2025 | -82.08 Mn |
| Jun 30, 2025 | -87.18 Mn |
| Mar 31, 2025 | -74.24 Mn |
| Dec 31, 2024 | -65.77 Mn |
| Sep 30, 2024 | -53.06 Mn |
| Jun 30, 2024 | -53.77 Mn |
| Mar 31, 2024 | -55.14 Mn |
| Dec 31, 2023 | -50.65 Mn |
| Sep 30, 2023 | -60.25 Mn |
| Jun 30, 2023 | -49.35 Mn |
| Mar 31, 2023 | -48.95 Mn |
| Dec 31, 2022 | -39.69 Mn |
| Sep 30, 2022 | -43.10 Mn |
| Jun 30, 2022 | -42.25 Mn |
| Mar 31, 2022 | -31.86 Mn |
| Dec 31, 2021 | -29.61 Mn |
| Sep 30, 2021 | -29.17 Mn |
| Jun 30, 2021 | -27.29 Mn |
| Mar 31, 2021 | -22.09 Mn |