Ultragenyx Pharmaceutical RARE
NASDAQ RARE
$15.28 +0.43 (+2.93%)
As of: Sep 4, 2026 · 3:59 PM EDT

Ultragenyx Pharmaceutical (RARE) Operating Income (2013 - 2026)

Ultragenyx Pharmaceutical (RARE) posted quarterly Operating Income of -$169.0 million for Q1 2026, down 18.18% year-over-year from -$206.6 million in Q1 2025, and down 49.18% quarter-over-quarter from -$113.3 million in Q4 2025.

Analysis

Ultragenyx Pharmaceutical (RARE) Operating Income (2013 - 2026) Analysis & Trends

Ultragenyx Pharmaceutical (RARE) has reported Operating Income for 14 consecutive years, with -$169.0 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Income fell 18.18% year-over-year to -$169.0 million; the TTM figure through Mar 2026 stood at -$561.1 million (down 9.23% YoY), while the FY2025 annual figure was -$535.0 million, changed 0.19% from the prior year.
  • Operating Income slipped to -$169.0 million in Q1 2026 per RARE's latest filing, from -$113.3 million in the prior quarter.
  • Across five years, Operating Income topped out at -$107.9 million in Q2 2025 and bottomed at -$225.1 million in Q3 2022.
  • Historically, Operating Income has averaged -$144.6 million across 5 years, with a median of -$143.0 million in 2025.
  • Annual changes were most pronounced in 2022 — Operating Income sank 150.55% — and 2023, when it soared 35.53%.
  • Ultragenyx Pharmaceutical's Operating Income stood at -$145.6 million in 2022, then climbed by 16.33% to -$121.8 million in 2023, then dropped by 0.38% to -$122.3 million in 2024, then climbed by 7.38% to -$113.3 million in 2025, then tumbled by 49.18% to -$169.0 million in 2026.
  • Business Quant data shows RARE's Operating Income at -$169.0 million in Q1 2026, -$113.3 million in Q4 2025, and -$170.9 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -505.13 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 133.12 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -1.55 Mn
10 Ultragenyx Pharmaceutical 1.56 Bn 1.27 Bn 180.00 Mn -75.00 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -75.00 Mn
Mar 31, 2026 -169.00 Mn
Dec 31, 2025 -113.28 Mn
Sep 30, 2025 -170.89 Mn
Jun 30, 2025 -108.00 Mn
Mar 31, 2025 -143.00 Mn
Dec 31, 2024 -122.31 Mn
Sep 30, 2024 -131.99 Mn
Jun 30, 2024 -116.36 Mn
Mar 31, 2024 -165.35 Mn
Dec 31, 2023 -121.84 Mn
Sep 30, 2023 -145.10 Mn
Jun 30, 2023 -147.96 Mn
Mar 31, 2023 -154.11 Mn
Dec 31, 2022 -145.63 Mn
Sep 30, 2022 -225.07 Mn
Jun 30, 2022 -141.59 Mn
Mar 31, 2022 -136.63 Mn
Dec 31, 2021 -102.56 Mn
Sep 30, 2021 -89.83 Mn