Ultragenyx Pharmaceutical (RARE) Operating Income (2013 - 2026)

Ultragenyx Pharmaceutical (RARE) reported Operating Income of -$169.0 million for Q1 2026, down 18.18% year-over-year from -$206.6 million in Q1 2025, and down 49.18% quarter-over-quarter from -$113.3 million in Q4 2025.

Ultragenyx Pharmaceutical (RARE) Operating Income (2013 - 2026) Analysis & Trends

Ultragenyx Pharmaceutical (RARE) has 14 years of Operating Income data on file, last reported at -$169.0 million in Q1 2026.

  • Operating Income for Q1 2026 came in at -$169.0 million, down 18.18% year-over-year; the trailing twelve-month figure through Mar 2026 was -$561.1 million (down 9.23% YoY), and the FY2025 annual result was -$535.0 million, changed 0.19% from the prior year.
  • Operating Income declined to -$169.0 million in Q1 2026 per RARE's latest filing, from -$113.3 million in the prior quarter.
  • Over five years, Operating Income peaked at -$107.9 million in Q2 2025 and troughed at -$225.1 million in Q3 2022.
  • A 5-year average of -$144.6 million and a median of -$143.0 million in 2025 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2022 and 2023: Operating Income sank 150.55% in 2022, then soared 35.53% in 2023.
  • A 5-year view of Operating Income shows it stood at -$145.6 million in 2022, then advanced by 16.33% to -$121.8 million in 2023, then slipped by 0.38% to -$122.3 million in 2024, then advanced by 7.38% to -$113.3 million in 2025, then slumped by 49.18% to -$169.0 million in 2026.
  • Business Quant data shows RARE's Operating Income at -$169.0 million in Q1 2026, -$113.3 million in Q4 2025, and -$170.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Ultragenyx Pharmaceutical 2.77 Bn 2.36 Bn 106.00 Mn -169.00 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -169.00 Mn
Dec 31, 2025 -113.28 Mn
Sep 30, 2025 -170.89 Mn
Jun 30, 2025 -107.89 Mn
Mar 31, 2025 -143.00 Mn
Dec 31, 2024 -122.31 Mn
Sep 30, 2024 -131.99 Mn
Jun 30, 2024 -116.36 Mn
Mar 31, 2024 -165.35 Mn
Dec 31, 2023 -121.84 Mn
Sep 30, 2023 -145.10 Mn
Jun 30, 2023 -147.96 Mn
Mar 31, 2023 -154.11 Mn
Dec 31, 2022 -145.63 Mn
Sep 30, 2022 -225.07 Mn
Jun 30, 2022 -141.59 Mn
Mar 31, 2022 -136.63 Mn
Dec 31, 2021 -102.56 Mn
Sep 30, 2021 -89.83 Mn
Jun 30, 2021 -82.78 Mn