Growth Metrics

Ultragenyx Pharmaceutical (RARE) Gross Profit (2018 - 2026)

Ultragenyx Pharmaceutical (RARE) reported Gross Profit of $106.0 million for Q1 2026, down 3.64% year-over-year from $110.0 million in Q1 2025, and down 40.43% on a QoQ basis from $177.9 million in Q4 2025.

Ultragenyx Pharmaceutical (RARE) has 9 years of Gross Profit data on file, last reported at $106.0 million in Q1 2026.

  • Quarterly Gross Profit fell 3.64% year-over-year to $106.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $559.4 million (up 11.49% YoY) and the FY2025 annual result came in at $564.0 million, up 16.77% from the prior year.
  • Gross Profit declined to $106.0 million in Q1 2026 per RARE's latest filing, from $177.9 million in the prior quarter.
  • Across five years, Gross Profit topped out at $177.9 million in Q4 2025 and bottomed at $73.8 million in Q1 2022.
  • The 5-year median for Gross Profit is $106.0 million (2026), against an average of $110.4 million.
  • The widest annual swing landed in 2022, when Gross Profit declined 21.62%; it then soared 36.07% in 2024.
  • Tracing RARE's Gross Profit over 5 years: stood at $98.0 million in 2022, then climbed by 17.62% to $115.3 million in 2023, then rose by 27.91% to $147.5 million in 2024, then increased by 20.65% to $177.9 million in 2025, then sank by 40.43% to $106.0 million in 2026.
  • Per Business Quant, the three latest RARE Gross Profit figures stand at $106.0 million (Q1 2026), $177.9 million (Q4 2025), and $131.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn
10 Ultragenyx Pharmaceutical 2.29 Bn 1.89 Bn 106.00 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 106.00 Mn
Mar 31, 2026 106.00 Mn
Dec 31, 2025 177.93 Mn
Dec 31, 2025 177.93 Mn
Sep 30, 2025 131.94 Mn
Sep 30, 2025 131.94 Mn
Jun 30, 2025 143.49 Mn
Jun 30, 2025 143.49 Mn
Mar 31, 2025 110.00 Mn
Mar 31, 2025 110.00 Mn
Dec 31, 2024 147.48 Mn
Dec 31, 2024 147.48 Mn
Sep 30, 2024 118.47 Mn
Sep 30, 2024 118.47 Mn
Jun 30, 2024 125.75 Mn
Jun 30, 2024 125.75 Mn
Mar 31, 2024 91.30 Mn
Mar 31, 2024 91.30 Mn
Dec 31, 2023 115.30 Mn
Dec 31, 2023 115.30 Mn
Sep 30, 2023 87.07 Mn
Sep 30, 2023 87.07 Mn
Jun 30, 2023 98.40 Mn
Jun 30, 2023 98.40 Mn
Mar 31, 2023 88.24 Mn
Mar 31, 2023 88.24 Mn
Dec 31, 2022 98.03 Mn
Dec 31, 2022 98.03 Mn
Sep 30, 2022 82.07 Mn
Sep 30, 2022 82.07 Mn
Jun 30, 2022 81.07 Mn
Jun 30, 2022 81.07 Mn
Mar 31, 2022 73.84 Mn
Mar 31, 2022 73.84 Mn
Dec 31, 2021 79.88 Mn
Dec 31, 2021 79.88 Mn
Sep 30, 2021 77.47 Mn
Sep 30, 2021 77.47 Mn
Jun 30, 2021 83.84 Mn
Jun 30, 2021 83.84 Mn
Mar 31, 2021 94.21 Mn
Mar 31, 2021 94.21 Mn
Dec 31, 2020 86.06 Mn
Dec 31, 2020 86.06 Mn
Sep 30, 2020 79.12 Mn
Sep 30, 2020 79.12 Mn
Jun 30, 2020 59.91 Mn
Jun 30, 2020 59.91 Mn
Mar 31, 2020 32.81 Mn
Mar 31, 2020 32.81 Mn
Dec 31, 2019 30.49 Mn
Dec 31, 2019 30.49 Mn
Sep 30, 2019 23.12 Mn
Sep 30, 2019 23.12 Mn
Jun 30, 2019 23.38 Mn
Jun 30, 2019 23.38 Mn
Mar 31, 2019 17.72 Mn
Mar 31, 2019 17.72 Mn
Dec 31, 2018 15.75 Mn
Dec 31, 2018 15.75 Mn
Sep 30, 2018 11.49 Mn
Sep 30, 2018 11.49 Mn
Jun 30, 2018 12.65 Mn
Jun 30, 2018 12.65 Mn
Mar 31, 2018 10.45 Mn
Mar 31, 2018 10.45 Mn