Growth Metrics

Ultragenyx Pharmaceutical (RARE) EBITDA (2013 - 2026)

Ultragenyx Pharmaceutical (RARE) reported EBITDA of -$169.0 million for Q1 2026, down 18.18% year-over-year from -$206.6 million in Q1 2025, and down 49.18% on a QoQ basis from -$113.3 million in Q4 2025.

Ultragenyx Pharmaceutical (RARE) has 14 years of EBITDA data on file, last reported at -$169.0 million in Q1 2026.

  • Quarterly EBITDA fell 18.18% year-over-year to -$169.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$561.1 million (down 9.23% YoY) and the FY2025 annual result came in at -$535.0 million, changed 0.19% from the prior year.
  • EBITDA fell to -$169.0 million in Q1 2026 per RARE's latest filing, from -$113.3 million in the prior quarter.
  • Across five years, EBITDA topped out at -$107.9 million in Q2 2025 and bottomed at -$225.1 million in Q3 2022.
  • The 5-year median for EBITDA is -$143.0 million (2025), against an average of -$144.6 million.
  • The widest annual swing landed in 2022, when EBITDA tumbled 150.55%; it then jumped 35.53% in 2023.
  • Tracing RARE's EBITDA over 5 years: stood at -$145.6 million in 2022, then rose by 16.33% to -$121.8 million in 2023, then retreated by 0.38% to -$122.3 million in 2024, then rose by 7.38% to -$113.3 million in 2025, then plunged by 49.18% to -$169.0 million in 2026.
  • Per Business Quant, the three latest RARE EBITDA figures stand at -$169.0 million (Q1 2026), -$113.3 million (Q4 2025), and -$170.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Ultragenyx Pharmaceutical 2.29 Bn 1.89 Bn 106.00 Mn -169.00 Mn

Historic Data

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DateValue
Mar 31, 2026 -169.00 Mn
Dec 31, 2025 -113.28 Mn
Sep 30, 2025 -170.89 Mn
Jun 30, 2025 -107.89 Mn
Mar 31, 2025 -143.00 Mn
Dec 31, 2024 -122.31 Mn
Sep 30, 2024 -131.99 Mn
Jun 30, 2024 -116.36 Mn
Mar 31, 2024 -165.35 Mn
Dec 31, 2023 -121.84 Mn
Sep 30, 2023 -145.10 Mn
Jun 30, 2023 -147.96 Mn
Mar 31, 2023 -154.11 Mn
Dec 31, 2022 -145.63 Mn
Sep 30, 2022 -225.07 Mn
Jun 30, 2022 -141.59 Mn
Mar 31, 2022 -136.63 Mn
Dec 31, 2021 -102.56 Mn
Sep 30, 2021 -89.83 Mn
Jun 30, 2021 -82.78 Mn
Mar 31, 2021 -106.57 Mn
Dec 31, 2020 -96.08 Mn
Sep 30, 2020 -50.32 Mn
Jun 30, 2020 -63.06 Mn
Mar 31, 2020 -120.67 Mn
Dec 31, 2019 -94.45 Mn
Sep 30, 2019 -118.03 Mn
Jun 30, 2019 -112.47 Mn
Mar 31, 2019 -99.21 Mn
Dec 31, 2018 -90.34 Mn
Sep 30, 2018 -89.65 Mn
Jun 30, 2018 -94.90 Mn
Mar 31, 2018 -96.49 Mn
Dec 31, 2017 -96.83 Mn
Sep 30, 2017 -83.71 Mn
Jun 30, 2017 -78.44 Mn
Mar 31, 2017 -68.96 Mn
Dec 31, 2016 -70.55 Mn
Sep 30, 2016 -65.78 Mn
Jun 30, 2016 -58.05 Mn
Mar 31, 2016 -51.80 Mn
Dec 31, 2015 -56.05 Mn
Sep 30, 2015 -39.06 Mn
Jun 30, 2015 -29.90 Mn
Mar 31, 2015 -21.30 Mn
Dec 31, 2014 -16.79 Mn
Sep 30, 2014 -15.92 Mn
Jun 30, 2014 -13.59 Mn
Mar 31, 2014 -13.69 Mn
Dec 31, 2013 -11.29 Mn
Sep 30, 2013 -8.37 Mn
Jun 30, 2013 -8.25 Mn
Mar 31, 2013 -6.75 Mn