Qiagen (QGEN) Operating Margin (2009 - 2025)
Qiagen (QGEN) posted Operating Margin of 18.4% for Q4 2025, down 24.13% sequentially from 24.25% in Q3 2025, and down 445.0% YoY from 5.33% in Q4 2024.
Qiagen (QGEN) Operating Margin (2009 - 2025) Analysis & Trends
Qiagen (QGEN) has 17 years of Operating Margin data on file, last reported at 18.4% in Q4 2025.
- Quarterly Operating Margin fell 445.0% year-over-year to 18.4% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 22.29% (up 1735.0% YoY) and the FY2025 annual result came in at 22.29%, up 1735.0% from the prior year.
- Operating Margin declined to 18.4% in Q4 2025 per QGEN's latest filing, from 24.25% in the prior quarter.
- The five-year high for Operating Margin was 131.73% in Q4 2022, with the low at 46.02% in Q2 2024.
- Average Operating Margin over 5 years is 25.66%, with a median of 22.85% recorded in 2025.
- Year-over-year, Operating Margin jumped 10200 bps in 2022 and sank 11001 bps in 2023.
- Qiagen's Operating Margin stood at 29.73% in 2021, then jumped by 343 bps to 131.73% in 2022, then plunged by 84 bps to 21.72% in 2023, then rose by 5 bps to 22.85% in 2024, then retreated by 19 bps to 18.4% in 2025.
- Business Quant data shows QGEN's Operating Margin at 18.4% in Q4 2025, 24.25% in Q3 2025, and 22.85% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | -3.71% |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 16.93% |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 22.58% |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 31.78% |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | -13.42% |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 21.74% |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 12.38% |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 19.16% |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 25.23% |
| 10 | Qiagen | 8.12 Bn | 7.47 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 18.40% |
| Sep 30, 2025 | 24.25% |
| Jun 30, 2025 | 22.85% |
| Mar 31, 2025 | 23.86% |
| Dec 31, 2024 | 22.85% |
| Sep 30, 2024 | 22.34% |
| Jun 30, 2024 | -46.02% |
| Mar 31, 2024 | 20.69% |
| Dec 31, 2023 | 21.72% |
| Sep 30, 2023 | 20.42% |
| Jun 30, 2023 | 21.31% |
| Mar 31, 2023 | 19.92% |
| Dec 31, 2022 | 21.00% |
| Sep 30, 2022 | 19.55% |
| Jun 30, 2022 | 23.70% |
| Mar 31, 2022 | 32.95% |
| Dec 31, 2021 | 29.73% |
| Jun 30, 2021 | 28.43% |
| Mar 31, 2021 | 28.88% |
| Dec 31, 2020 | 27.29% |