Qiagen (QGEN) Operating Margin (2009 - 2025)
Qiagen (QGEN) posted Operating Margin of 18.4% for Q4 2025, down 24.13% sequentially from 24.25% in Q3 2025, and up 593.0% YoY from 2.66% in Q4 2024.
Qiagen (QGEN) Operating Margin (2009 - 2025) Analysis & Trends
Qiagen has reported Operating Margin for 17 years, with the latest figure at 18.4% in Q4 2025.
- Quarterly Operating Margin rose 593.0% year-over-year to 18.4% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 22.29% (up 1824.0% YoY) and the FY2025 annual result came in at 22.29%, up 1735.0% from the prior year.
- Operating Margin declined to 18.4% in Q4 2025 per QGEN's latest filing, from 24.25% in the prior quarter.
- Over five years, Operating Margin peaked at 32.95% in Q1 2022 and troughed at 46.02% in Q2 2024.
- A 5-year average of 18.52% and a median of 21.31% in 2023 frame the typical range for Operating Margin.
- The sharpest annual moves came in 2024 and 2025: Operating Margin plunged 6733 bps in 2024, then jumped 6887 bps in 2025.
- Over 5 years, Operating Margin stood at 15.25% in 2021, then surged by 38 bps to 21.0% in 2022, then advanced by 3 bps to 21.72% in 2023, then plunged by 43 bps to 12.47% in 2024, then soared by 48 bps to 18.4% in 2025.
- According to Business Quant data, Operating Margin over the past three periods registered 18.4%, 24.25%, and 22.85% for Q4 2025, Q3 2025, and Q2 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.40 Bn | 209.33 Bn | 8.34 Bn | 17.40% |
| 2 | Danaher | 139.94 Bn | 135.59 Bn | 3.61 Bn | 17.99% |
| 3 | Idexx Laboratories | 46.03 Bn | 45.83 Bn | 779.09 Mn | 34.98% |
| 4 | Agilent Technologies | 39.69 Bn | 37.88 Bn | 990.00 Mn | 21.74% |
| 5 | Iqvia Holdings | 39.32 Bn | 37.24 Bn | 1.44 Bn | 11.58% |
| 6 | Natera | 38.47 Bn | 37.37 Bn | 696.04 Mn | -13.42% |
| 7 | Illumina | 29.98 Bn | 28.82 Bn | 770.00 Mn | 21.14% |
| 8 | Mettler Toledo International | 28.57 Bn | 28.52 Bn | 650.22 Mn | 31.97% |
| 9 | Quest Diagnostics | 26.21 Bn | 25.58 Bn | 1.03 Bn | 15.08% |
| 10 | Qiagen | 8.62 Bn | 8.62 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 18.40% |
| Sep 30, 2025 | 24.25% |
| Jun 30, 2025 | 22.85% |
| Mar 31, 2025 | 23.86% |
| Dec 31, 2024 | 12.47% |
| Sep 30, 2024 | 22.34% |
| Jun 30, 2024 | -46.02% |
| Mar 31, 2024 | 20.69% |
| Dec 31, 2023 | 21.72% |
| Sep 30, 2023 | 20.42% |
| Jun 30, 2023 | 21.31% |
| Mar 31, 2023 | 19.92% |
| Dec 31, 2022 | 21.00% |
| Sep 30, 2022 | 19.55% |
| Jun 30, 2022 | 23.70% |
| Mar 31, 2022 | 32.95% |
| Dec 31, 2021 | 15.25% |
| Jun 30, 2021 | 28.43% |
| Mar 31, 2021 | 28.88% |
| Dec 31, 2020 | 27.29% |