Qiagen (QGEN) Operating Margin (2009 - 2025)
Qiagen's (QGEN) quarterly Operating Margin came in at 18.4% in Q4 2025, down 445.0% year-on-year from 5.33% in Q4 2024, and down 24.13% quarter-over-quarter from 24.25% in Q3 2025.
Qiagen (QGEN) Operating Margin (2009 - 2025) Analysis & Trends
Qiagen has disclosed Operating Margin across 17 years of filings, most recently posting 18.4% for Q4 2025.
- Operating Margin for Q4 2025 came in at 18.4%, down 445.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 22.29% (up 1735.0% YoY), and the FY2025 annual result was 22.29%, up 1735.0% from the prior year.
- Operating Margin came in at 18.4% for Q4 2025 at Qiagen, down from 24.25% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 32.95% in Q1 2022 to a low of 46.02% in Q2 2024.
- The 5-year median for Operating Margin is 22.34% (2024), against an average of 19.83%.
- Across the five-year window, Operating Margin plunged 6733 bps in 2024 and surged 6887 bps in 2025, its largest moves.
- Qiagen's Operating Margin stood at 29.73% in 2021, then fell by 29 bps to 21.0% in 2022, then rose by 3 bps to 21.72% in 2023, then climbed by 5 bps to 22.85% in 2024, then dropped by 19 bps to 18.4% in 2025.
- The last three Operating Margin figures came in at 18.4% (Q4 2025), 24.25% (Q3 2025), and 22.85% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 30,529.42 Bn | 30,528.96 Bn | 1.11 Bn | -3.71% |
| 2 | Thermo Fisher Scientific | 183.75 Bn | 180.50 Bn | 7.74 Bn | 16.93% |
| 3 | Danaher | 133.13 Bn | 127.43 Bn | 3.59 Bn | 22.58% |
| 4 | Idexx Laboratories | 46.14 Bn | 45.94 Bn | 722.74 Mn | 31.78% |
| 5 | Agilent Technologies | 38.20 Bn | 36.39 Bn | 990.00 Mn | 21.74% |
| 6 | Natera | 31.50 Bn | 30.40 Bn | 696.04 Mn | -13.42% |
| 7 | Iqvia Holdings | 31.34 Bn | 29.36 Bn | 1.36 Bn | 12.38% |
| 8 | Illumina | 24.51 Bn | 23.36 Bn | 721.00 Mn | 19.16% |
| 9 | Mettler Toledo International | 23.53 Bn | 23.47 Bn | 555.82 Mn | 25.23% |
| 10 | Qiagen | 8.54 Bn | 7.44 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 18.40% |
| Sep 30, 2025 | 24.25% |
| Jun 30, 2025 | 22.85% |
| Mar 31, 2025 | 23.86% |
| Dec 31, 2024 | 22.85% |
| Sep 30, 2024 | 22.34% |
| Jun 30, 2024 | -46.02% |
| Mar 31, 2024 | 20.69% |
| Dec 31, 2023 | 21.72% |
| Sep 30, 2023 | 20.42% |
| Jun 30, 2023 | 21.31% |
| Mar 31, 2023 | 19.92% |
| Dec 31, 2022 | 21.00% |
| Sep 30, 2022 | 19.55% |
| Jun 30, 2022 | 23.70% |
| Mar 31, 2022 | 32.95% |
| Dec 31, 2021 | 29.73% |
| Jun 30, 2021 | 28.43% |
| Mar 31, 2021 | 28.88% |
| Dec 31, 2020 | 27.29% |