PolyPid PYPD
NASDAQ PYPD
$5.10 +0.02 (+0.39%)
At close: Aug 21, 2026 · 4:00 PM EDT

PolyPid (PYPD) Return on Invested Capital (2023 - 2025)

PolyPid (PYPD) posted Return on Invested Capital of 0.02% for Q4 2025, up 23.62% sequentially from 0.01% in Q3 2025, and little changed YoY from 0.02% in Q4 2024.

PolyPid (PYPD) Return on Invested Capital (2023 - 2025) Analysis & Trends

PolyPid has reported Return on Invested Capital for 3 years, with the latest figure at 0.02% in Q4 2025.

  • Quarterly Return on Invested Capital changed 0.0% year-over-year to 0.02% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 0.02% (changed 0.0% YoY) and the FY2025 annual result came in at 0.08%, down 3.0% from the prior year.
  • Return on Invested Capital grew to 0.02% in Q4 2025 per PYPD's latest filing, from 0.01% in the prior quarter.
  • Over five years, Return on Invested Capital peaked at 0.02% in Q2 2023 and troughed at 0.01% in Q1 2025.
  • A 3-year average of 0.02% and a median of 0.02% in 2024 frame the typical range for Return on Invested Capital.
  • The widest YoY moves for Return on Invested Capital: up 0 bps in 2024, down 0 bps in 2024.
  • Over 3 years, Return on Invested Capital stood at 0.02% in 2023, then fell by 21 bps to 0.01% in 2024, then advanced by 24 bps to 0.02% in 2025.
  • According to Business Quant data, Return on Invested Capital over the past three periods registered 0.02%, 0.01%, and 0.01% for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROIC (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn -
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 0.04%
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -0.17%
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 0.00%
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn -
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 0.00%
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -0.35%
9 Royalty Pharma 27.27 Bn 26.43 Bn - -
10 PolyPid 113.86 Mn 107.09 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 0.02%
Sep 30, 2025 0.01%
Jun 30, 2025 0.01%
Mar 31, 2025 0.01%
Dec 31, 2024 0.01%
Sep 30, 2024 0.01%
Jun 30, 2024 0.02%
Mar 31, 2024 0.02%
Dec 31, 2023 0.02%
Sep 30, 2023 0.02%
Jun 30, 2023 0.02%