Growth Metrics

Palvella Therapeutics (PVLA) EBITDA (2013 - 2026)

Palvella Therapeutics (PVLA) reported EBITDA of -$15.8 million for Q1 2026, down 92.35% year-over-year from -$205.8 million in Q1 2025, and down 23.71% on a QoQ basis from -$12.7 million in Q4 2025.

Palvella Therapeutics (PVLA) has 14 years of EBITDA data on file, last reported at -$15.8 million in Q1 2026.

  • Quarterly EBITDA fell 92.35% year-over-year to -$15.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$49.2 million (down 114.92% YoY) and the FY2025 annual result came in at -$41.6 million, down 138.86% from the prior year.
  • EBITDA retreated to -$15.8 million in Q1 2026 per PVLA's latest filing, from -$12.7 million in the prior quarter.
  • Across five years, EBITDA topped out at $38.0 million in Q4 2023 and bottomed at -$15.8 million in Q1 2026.
  • The 5-year median for EBITDA is -$8.9 million (2025), against an average of -$5.1 million.
  • The widest annual swing landed in 2023, when EBITDA soared 139.99%; it then plunged 278.34% in 2025.
  • Tracing PVLA's EBITDA over 5 years: stood at -$9.8 million in 2022, then surged by 485.88% to $38.0 million in 2023, then slumped by 108.87% to -$3.4 million in 2024, then sank by 278.34% to -$12.7 million in 2025, then fell by 23.71% to -$15.8 million in 2026.
  • Per Business Quant, the three latest PVLA EBITDA figures stand at -$15.8 million (Q1 2026), -$12.7 million (Q4 2025), and -$11.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Palvella Therapeutics 1.47 Bn 1.21 Bn - -15.76 Mn

Historic Data

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DateValue
Mar 31, 2026 -15.76 Mn
Dec 31, 2025 -12.74 Mn
Sep 30, 2025 -11.13 Mn
Jun 30, 2025 -9.58 Mn
Mar 31, 2025 -8.19 Mn
Dec 31, 2024 -3.37 Mn
Sep 30, 2024 -6.97 Mn
Jun 30, 2024 -4.37 Mn
Mar 31, 2024 -2.73 Mn
Dec 31, 2023 37.96 Mn
Sep 30, 2023 -10.95 Mn
Jun 30, 2023 4.27 Mn
Mar 31, 2023 -13.36 Mn
Sep 30, 2022 -9.84 Mn
Jun 30, 2022 -10.67 Mn
Mar 31, 2022 -4.98 Mn
Dec 31, 2021 -9.32 Mn
Sep 30, 2021 -16.15 Mn
Jun 30, 2021 -15.46 Mn
Mar 31, 2021 -3.68 Mn
Dec 31, 2020 -13.91 Mn
Sep 30, 2020 -14.00 Mn
Jun 30, 2020 -4.79 Mn
Mar 31, 2020 -2.83 Mn
Dec 31, 2019 -2.07 Mn
Sep 30, 2019 -582,000.00
Jun 30, 2019 -12.41 Mn
Mar 31, 2019 -9.42 Mn
Dec 31, 2018 -11.61 Mn
Sep 30, 2018 -6.63 Mn
Jun 30, 2018 3.20 Mn
Mar 31, 2018 -9.99 Mn
Dec 31, 2017 5.28 Mn
Sep 30, 2017 -7.45 Mn
Jun 30, 2017 -10.73 Mn
Mar 31, 2017 -7.94 Mn
Dec 31, 2016 -6.40 Mn
Sep 30, 2016 -6.18 Mn
Jun 30, 2016 -5.80 Mn
Mar 31, 2016 -4.38 Mn
Dec 31, 2015 -2.57 Mn
Sep 30, 2015 -3.88 Mn
Jun 30, 2015 -3.53 Mn
Mar 31, 2015 -3.70 Mn
Sep 30, 2014 -1.84 Mn
Jun 30, 2014 -2.77 Mn
Mar 31, 2014 -671,217.00
Dec 31, 2013 -2,198.00
Sep 30, 2013 -5,762.00
Jun 30, 2013 -274.00