Protagonist Therapeutics (PTGX) Return on Sales [ROS] (2017 - 2026)
Protagonist Therapeutics' Return on Sales [ROS] was 74.37% in Q2 2026, up 832.41 percentage points from -758.04% a year earlier and up 80.84 percentage points from the prior quarter.
Protagonist Therapeutics (PTGX) Return on Sales [ROS] (2017 - 2026) Analysis & Trends
On a trailing twelve-month basis, Protagonist Therapeutics' Return on Sales [ROS] was 20.69% through Jun 30, 2026, up 9.23 percentage points year-over-year; for FY2025, it came in at -343.63%, down 401.84 percentage points from FY2024.
- Return on Sales [ROS] shows a five-year change of -118.28 percentage points (FY2020 to FY2025).
- In earlier years, Return on Sales [ROS] was 58.20% in FY2024 (+214.29 pp), -156.09% in FY2023 (+338.15 pp), -494.24% in FY2022 (-34.23 pp) and -460.01% in FY2021 (-234.65 pp).
- The Q2 2026 figure marks the highest quarterly Return on Sales [ROS] since Q1 2024.
- Compared with a year earlier, Return on Sales [ROS] was higher in four of the last seven quarters, with an average year-over-year change of +14.85 percentage points.
- The best year-over-year quarter for Return on Sales [ROS] over five years was Q1 2024 (a gain of 16685.12 percentage points); the worst was Q1 2023 (a drop of 16522.13 percentage points).
- Per Business Quant data, PTGX's Return on Sales [ROS] in the three quarters before Q2 2026 was -6.47% (Q1 2026), -677.09% (Q4 2025) and -985.17% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Protagonist Therapeutics | 8.89 Bn | 6.19 Bn | 273.31 Mn | 79.56% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 79.56% |
| Jun 30, 2026 | 74.37% |
| Mar 31, 2026 | -6.47% |
| Dec 31, 2025 | -677.09% |
| Sep 30, 2025 | -985.17% |
| Jun 30, 2025 | -758.04% |
| Mar 31, 2025 | -68.18% |
| Dec 31, 2024 | 74.30% |
| Sep 30, 2024 | -886.70% |
| Jun 30, 2024 | -930.96% |
| Mar 31, 2024 | 80.92% |
| Dec 31, 2023 | 38.42% |
| Mar 31, 2023 | -16,604.20% |
| Dec 31, 2022 | -493.83% |
| Sep 30, 2022 | -374.22% |
| Jun 30, 2022 | -4,604.78% |
| Mar 31, 2022 | -82.07% |
| Dec 31, 2021 | -429.57% |
| Sep 30, 2021 | -329.83% |
| Jun 30, 2021 | -1,363.44% |
Protagonist Therapeutics Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=PTGX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "PTGX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=PTGX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();