Personalis (PSNL) Return on Invested Capital [ROIC] (2021 - 2026)
Personalis (PSNL) recorded Return on Invested Capital [ROIC] of -46.50% in Q2 2026, down 10.75 percentage points from -35.74% a year earlier and down 6.91 percentage points from the prior quarter.
Powered by 
Analysis
Personalis (PSNL) Return on Invested Capital [ROIC] (2021 - 2026) Analysis & Trends
For FY2025, Personalis reported Return on Invested Capital [ROIC] of -37.71%, up 2.96 percentage points from FY2024.
- Annual Return on Invested Capital [ROIC] has a three-year change of +5.68 percentage points (FY2022 to FY2025).
- Across earlier years, Return on Invested Capital [ROIC] came in at -40.67% in FY2024 (+21.89 pp), -62.56% in FY2023 (-19.17 pp) and -43.39% in FY2022.
- The Q2 2026 figure is the lowest quarterly Return on Invested Capital [ROIC] since Q3 2024.
- On a year-over-year basis, Return on Invested Capital [ROIC] has declined for three consecutive quarters, with an average year-over-year change of +16.71 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Invested Capital [ROIC] in the last five years was a gain of 45.78 percentage points in Q1 2025, against a drop of 31.37 percentage points in Q3 2023 at the low end.
- Per Business Quant, the preceding three quarters came in at -39.58% (Q1 2026), -40.46% (Q4 2025) and -44.26% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 102.25 Bn | 101.69 Bn | - | 22.01% |
| 2 | Natera | 58.01 Bn | 53.69 Bn | 485.19 Mn | -11.74% |
| 3 | Labcorp Holdings | 26.62 Bn | 24.38 Bn | 1.11 Bn | 8.25% |
| 4 | Quest Diagnostics | 26.61 Bn | 24.70 Bn | 1.04 Bn | 9.85% |
| 5 | Guardant Health | 22.59 Bn | 18.65 Bn | 219.03 Mn | - |
| 6 | Tenet Healthcare | 21.62 Bn | 12.76 Bn | - | 18.77% |
| 7 | Fresenius Medical Care AG | 12.67 Bn | 5.74 Bn | 1.52 Bn | 0.24% |
| 8 | Encompass Health | 12.25 Bn | 12.72 Bn | - | 15.40% |
| 9 | BrightSpring Health Services | 11.87 Bn | 10.21 Bn | 492.75 Mn | 8.62% |
| 10 | Personalis | 1.69 Bn | 849.58 Mn | 4.74 Mn | -46.50% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -46.50% |
| Mar 31, 2026 | -39.58% |
| Dec 31, 2025 | -40.46% |
| Sep 30, 2025 | -44.26% |
| Jun 30, 2025 | -35.74% |
| Mar 31, 2025 | -32.34% |
| Dec 31, 2024 | -36.64% |
| Sep 30, 2024 | -52.60% |
| Jun 30, 2024 | -76.67% |
| Mar 31, 2024 | -78.12% |
| Dec 31, 2023 | -77.78% |
| Sep 30, 2023 | -71.95% |
| Jun 30, 2023 | -61.50% |
| Mar 31, 2023 | -56.24% |
| Dec 31, 2022 | -49.70% |
| Sep 30, 2022 | -40.58% |
| Jun 30, 2022 | -33.92% |
| Mar 31, 2022 | -27.03% |
| Dec 31, 2021 | -20.45% |
| Sep 30, 2021 | -17.50% |
API Access
Personalis Return on Invested Capital [ROIC] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=PSNL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-invested-capital-[roic]", "ticker": "PSNL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=PSNL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();