Personalis (PSNL) EBITDA Margin (2018 - 2026)
Personalis (PSNL) recorded EBITDA Margin of -139.45% in Q2 2026, down 27.24 percentage points from -112.21% a year earlier but up 53.09 percentage points from the prior quarter.
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Analysis
Personalis (PSNL) EBITDA Margin (2018 - 2026) Analysis & Trends
On a TTM basis, Personalis' EBITDA Margin came in at -150.13% as of Jun 30, 2026, down 73.48 percentage points year-over-year; for FY2025, it came in at -112.01%, down 44.26 percentage points from FY2024.
- Annual EBITDA Margin has a five-year change of -65.79 percentage points (FY2020 to FY2025).
- Across earlier years, EBITDA Margin came in at -67.75% in FY2024 (+66.48 pp), -134.23% in FY2023 (+30.42 pp), -164.65% in FY2022 (-95.24 pp) and -69.41% in FY2021 (-23.19 pp).
- Quarterly EBITDA Margin has ranged from -192.54% in Q1 2026 to -45.05% in Q3 2024 over the past five years.
- On a year-over-year basis, EBITDA Margin has declined for five consecutive quarters, with an average year-over-year change of -25.26 percentage points over the last eight quarters.
- Peak year-over-year performance for EBITDA Margin in the last five years was a gain of 108.36 percentage points in Q3 2024, against a drop of 121.55 percentage points in Q1 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -192.54% (Q1 2026), -131.47% (Q4 2025) and -143.67% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 101.22 Bn | 97.23 Bn | - | 20.01% |
| 2 | Natera | 59.29 Bn | 54.98 Bn | 485.19 Mn | -7.25% |
| 3 | Quest Diagnostics | 26.56 Bn | 24.69 Bn | 1.03 Bn | 19.88% |
| 4 | Labcorp Holdings | 26.41 Bn | 24.16 Bn | 1.11 Bn | 16.90% |
| 5 | Tenet Healthcare | 22.49 Bn | 11.49 Bn | - | 30.60% |
| 6 | Guardant Health | 22.12 Bn | 18.19 Bn | 219.03 Mn | -35.69% |
| 7 | BrightSpring Health Services | 12.91 Bn | 11.24 Bn | 492.75 Mn | 4.51% |
| 8 | Fresenius Medical Care AG | 12.56 Bn | 4.51 Bn | 1.52 Bn | 16.93% |
| 9 | Tempus AI | 12.17 Bn | 9.20 Bn | 246.50 Mn | - |
| 10 | Personalis | 1.68 Bn | 845.71 Mn | 4.74 Mn | -139.45% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -139.45% |
| Mar 31, 2026 | -192.54% |
| Dec 31, 2025 | -131.47% |
| Sep 30, 2025 | -143.67% |
| Jun 30, 2025 | -112.21% |
| Mar 31, 2025 | -73.33% |
| Dec 31, 2024 | -92.67% |
| Sep 30, 2024 | -45.05% |
| Jun 30, 2024 | -62.41% |
| Mar 31, 2024 | -82.17% |
| Dec 31, 2023 | -107.10% |
| Sep 30, 2023 | -153.41% |
| Jun 30, 2023 | -135.01% |
| Mar 31, 2023 | -143.29% |
| Dec 31, 2022 | -174.34% |
| Sep 30, 2022 | -170.68% |
| Jun 30, 2022 | -142.99% |
| Mar 31, 2022 | -174.07% |
| Dec 31, 2021 | -90.05% |
| Sep 30, 2021 | -72.73% |
API Access
Personalis EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "PSNL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();