Growth Metrics

Personalis (PSNL) EBITDA Margin (2018 - 2026)

Personalis has reported EBITDA Margin over the past 8 years, most recently at 145.67% for Q4 2025.

  • For Q4 2025, EBITDA Margin fell 34263.0% year-over-year to 145.67%; the TTM value through Dec 2025 reached 126.43%, down 10626.0%, while the annual FY2025 figure was 126.43%, 10626.0% down from the prior year.
  • EBITDA Margin for Q4 2025 was 145.67% at Personalis, up from 160.68% in the prior quarter.
  • Over five years, EBITDA Margin peaked at 196.96% in Q4 2024 and troughed at 191.87% in Q4 2022.
  • A 5-year average of 108.51% and a median of 124.29% in 2023 define the central range for EBITDA Margin.
  • Biggest five-year swings in EBITDA Margin: soared 31880bps in 2024 and later tumbled -34263bps in 2025.
  • Year by year, EBITDA Margin stood at 97.79% in 2021, then tumbled by -96bps to 191.87% in 2022, then soared by 36bps to 121.84% in 2023, then soared by 262bps to 196.96% in 2024, then tumbled by -174bps to 145.67% in 2025.
  • Business Quant data shows EBITDA Margin for PSNL at 145.67% in Q4 2025, 160.68% in Q3 2025, and 126.75% in Q2 2025.