Growth Metrics

Protalix BioTherapeutics (PLX) Retained Earnings (2010 - 2025)

Protalix BioTherapeutics' quarterly Retained Earnings came in at -$385.0 million in Q4 2025, down 1.75% year-on-year from -$391.8 million in Q4 2024, and down 1.75% quarter-over-quarter from -$378.4 million in Q4 2024.

Protalix BioTherapeutics has reported Retained Earnings for 16 years, with the latest figure at -$385.0 million in Q4 2025.

  • For the quarter ending Q4 2025, Retained Earnings fell 1.75% year-over-year to -$385.0 million; the trailing twelve-month figure through Dec 2025 stood at -$385.0 million (down 1.75% YoY), and the FY2025 full-year result was -$385.0 million, down 1.75% from the prior year.
  • Retained Earnings for Q4 2025 stood at -$385.0 million, down from -$378.4 million in the prior quarter.
  • The five-year high for Retained Earnings was -$374.9 million in Q4 2021, with the low at -$389.9 million in Q4 2022.
  • Average Retained Earnings over 5 years is -$381.9 million, with a median of -$381.5 million recorded in 2023.
  • Year-over-year, Retained Earnings fell 7.94% in 2021 and gained 2.13% in 2023.
  • Tracing PLX's Retained Earnings over 5 years: stood at -$374.9 million in 2021, then slipped by 3.98% to -$389.9 million in 2022, then climbed by 2.13% to -$381.5 million in 2023, then climbed by 0.83% to -$378.4 million in 2024, then dropped by 1.75% to -$385.0 million in 2025.
  • The last three Retained Earnings figures came in at -$385.0 million (Q4 2025), -$378.4 million (Q4 2024), and -$381.5 million (Q4 2023), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -211.85 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -153.89 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 1.00 Bn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -438.66 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -279.00 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 14.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 130.89 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 36.42 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -24.89 Mn
10 Protalix BioTherapeutics 164.49 Mn 153.70 Mn 29.62 Mn -

Historic Data

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DateValue
Dec 31, 2025 -385.00 Mn
Dec 31, 2024 -378.39 Mn
Dec 31, 2023 -381.55 Mn
Dec 31, 2022 -389.86 Mn
Dec 31, 2021 -374.93 Mn
Dec 31, 2020 -347.35 Mn
Dec 31, 2019 -340.83 Mn
Dec 31, 2018 -322.55 Mn
Dec 31, 2017 -296.10 Mn
Dec 31, 2016 -212.66 Mn
Dec 31, 2015 -183.29 Mn
Dec 31, 2014 -241.33 Mn
Dec 31, 2013 -211.39 Mn
Dec 31, 2012 -183.60 Mn
Dec 31, 2011 -171.98 Mn
Dec 31, 2010 -135.45 Mn