Vaxcyte (PCVX) EBITDA (2019 - 2026)

Vaxcyte's (PCVX) quarterly EBITDA came in at -$345.8 million in Q1 2026, down 91.3% year-on-year from -$4.0 billion in Q1 2025, and down 26.09% on a QoQ basis from -$274.3 million in Q4 2025.

Vaxcyte (PCVX) EBITDA (2019 - 2026) Analysis & Trends

Vaxcyte (PCVX) has 8 years of EBITDA data on file, last reported at -$345.8 million in Q1 2026.

  • On a quarterly basis, EBITDA fell 91.3% year-over-year to -$345.8 million in Q1 2026; TTM through Mar 2026 was -$1.1 billion, a 71.22% decrease from a year earlier, with the FY2025 full-year figure at -$923.7 million, down 62.18% from the prior year.
  • EBITDA for Q1 2026 stood at -$345.8 million, down from -$274.3 million in the prior quarter.
  • Over the last five years, EBITDA for PCVX reached as high as -$39.2 million in Q1 2022 and fell as low as -$345.8 million in Q1 2026.
  • Historically, EBITDA has averaged -$149.4 million across 5 years, with a median of -$139.9 million in 2024.
  • Across the five-year window, EBITDA slumped 190.07% in 2022 and rose 17.55% in 2024, its largest moves.
  • Year by year, EBITDA stood at -$86.6 million in 2022, then plunged by 127.18% to -$196.7 million in 2023, then advanced by 17.55% to -$162.2 million in 2024, then plunged by 69.13% to -$274.3 million in 2025, then retreated by 26.09% to -$345.8 million in 2026.
  • Per Business Quant data, the three most recent EBITDA figures were -$345.8 million in Q1 2026, -$274.3 million in Q4 2025, and -$242.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Vaxcyte 7.76 Bn 7.76 Bn - -345.85 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -345.85 Mn
Dec 31, 2025 -274.28 Mn
Sep 30, 2025 -242.38 Mn
Jun 30, 2025 -226.22 Mn
Mar 31, 2025 -180.79 Mn
Dec 31, 2024 -162.17 Mn
Sep 30, 2024 -139.92 Mn
Jun 30, 2024 -152.98 Mn
Mar 31, 2024 -114.47 Mn
Dec 31, 2023 -196.68 Mn
Sep 30, 2023 -113.03 Mn
Jun 30, 2023 -87.15 Mn
Mar 31, 2023 -71.19 Mn
Dec 31, 2022 -86.57 Mn
Sep 30, 2022 -58.58 Mn
Jun 30, 2022 -47.89 Mn
Mar 31, 2022 -39.22 Mn
Dec 31, 2021 -29.85 Mn
Sep 30, 2021 -26.95 Mn
Jun 30, 2021 -23.73 Mn