NuCana (NCNA) Enterprise Value (2015 - 2025)

NuCana (NCNA) reported Enterprise Value of -$32.3 million for Q4 2025, down 272.39% on a YoY basis from $18.7 million in Q4 2024, and up 5.32% sequentially from -$34.1 million in Q3 2025.

NuCana (NCNA) Enterprise Value (2015 - 2025) Analysis & Trends

NuCana (NCNA) has 11 years of Enterprise Value data on file, last reported at -$32.3 million in Q4 2025.

  • For the quarter ending Q4 2025, Enterprise Value fell 272.39% year-over-year to -$32.3 million; the trailing twelve-month figure through Dec 2025 stood at -$32.3 million (down 272.39% YoY), and the FY2025 full-year result was -$32.0 million, down 270.64% from the prior year.
  • Enterprise Value improved to -$32.3 million in Q4 2025, from -$34.1 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$5.0 million in Q1 2025 to a low of -$108.4 million in Q1 2021.
  • A 5-year average of -$44.1 million and a median of -$33.2 million in 2025 frame the typical range for Enterprise Value.
  • Peak annual rise in Enterprise Value reached 69.5% in 2025, while the deepest fall reached 272.39% in 2025.
  • Tracing NCNA's Enterprise Value over 5 years: stood at -$81.2 million in 2021, then jumped by 39.49% to -$49.2 million in 2022, then soared by 56.51% to -$21.4 million in 2023, then soared by 59.48% to -$8.7 million in 2024, then tumbled by 272.39% to -$32.3 million in 2025.
  • Business Quant data shows NCNA's Enterprise Value at -$32.3 million in Q4 2025, -$34.1 million in Q3 2025, and -$14.7 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn -3.01 Bn

Historic Data

Download Data
DateValue
Dec 31, 2025 -32.26 Mn
Sep 30, 2025 -34.07 Mn
Jun 30, 2025 -14.74 Mn
Mar 31, 2025 -4.98 Mn
Dec 31, 2024 -8.66 Mn
Sep 30, 2024 -14.75 Mn
Jun 30, 2024 -14.69 Mn
Mar 31, 2024 -16.32 Mn
Dec 31, 2023 -21.38 Mn
Sep 30, 2023 -22.55 Mn
Jun 30, 2023 -30.84 Mn
Mar 31, 2023 -37.68 Mn
Dec 31, 2022 -49.16 Mn
Sep 30, 2022 -59.81 Mn
Jun 30, 2022 -58.59 Mn
Mar 31, 2022 -70.53 Mn
Dec 31, 2021 -81.24 Mn
Sep 30, 2021 -97.92 Mn
Jun 30, 2021 -102.62 Mn
Mar 31, 2021 -108.42 Mn