MapLight Therapeutics (MPLT) Operating Income (2024 - 2025)
MapLight Therapeutics' (MPLT) quarterly Operating Income came in at -$83.4 million in Q4 2025, down 266.06% year-on-year from $50.2 million in Q4 2024, and down 164.71% quarter-over-quarter from -$31.5 million in Q3 2025.
MapLight Therapeutics (MPLT) Operating Income (2024 - 2025) Analysis & Trends
MapLight Therapeutics has disclosed Operating Income across 2 years of filings, most recently posting -$83.4 million for Q4 2025.
- Operating Income for Q4 2025 came in at -$83.4 million, down 266.06% year-over-year; the trailing twelve-month figure through Dec 2025 was -$158.5 million (changed N/A YoY), and the FY2025 annual result was -$169.1 million, down 103.85% from the prior year.
- Operating Income came in at -$83.4 million for Q4 2025 at MapLight Therapeutics, down from -$31.5 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$20.9 million in Q3 2024 to a low of -$83.4 million in Q4 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | MapLight Therapeutics | 248.88 Mn | 248.88 Mn | - | -83.38 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -83.38 Mn |
| Sep 30, 2025 | -31.50 Mn |
| Dec 31, 2024 | -22.78 Mn |
| Sep 30, 2024 | -20.89 Mn |