MapLight Therapeutics (MPLT) EBITDA (2024 - 2025)

MapLight Therapeutics recorded quarterly EBITDA of -$79.8 million in Q4 2025, down 171.3% quarter-over-quarter from -$29.4 million in Q3 2025, and down 271.37% year-over-year from $46.6 million in Q4 2024.

MapLight Therapeutics' EBITDA history runs 2 years deep, the most recent figure standing at -$79.8 million for Q4 2025.

  • In Q4 2025, EBITDA fell 271.37% year-over-year to -$79.8 million; the TTM figure through Dec 2025 stood at -$149.1 million (changed N/A YoY), while the FY2025 annual figure was -$161.5 million, down 108.67% from the prior year.
  • EBITDA came in at -$79.8 million for Q4 2025 at MapLight Therapeutics, down from -$29.4 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$18.4 million in Q3 2024 to a low of -$79.8 million in Q4 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 MapLight Therapeutics 254.43 Mn 254.43 Mn - -79.82 Mn

Historic Data

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DateValue
Dec 31, 2025 -79.82 Mn
Sep 30, 2025 -29.42 Mn
Dec 31, 2024 -21.49 Mn
Sep 30, 2024 -18.40 Mn