Monopar Therapeutics (MNPR) Operating Income (2017 - 2025)

Monopar Therapeutics' (MNPR) quarterly Operating Income came in at -$4.1 million in Q3 2025, down 159.89% year-on-year from $6.8 million in Q3 2024, and down 26.55% quarter-over-quarter from -$3.2 million in Q2 2025.

Monopar Therapeutics (MNPR) Operating Income (2017 - 2025) Analysis & Trends

Monopar Therapeutics has disclosed Operating Income across 9 years of filings, most recently posting -$4.1 million for Q3 2025.

  • Operating Income for Q3 2025 came in at -$4.1 million, down 159.89% year-over-year; the trailing twelve-month figure through Sep 2025 was -$12.1 million (down 69.49% YoY), and the FY2022 annual result was -$10.5 million, down 15.44% from the prior year.
  • Operating Income came in at -$4.1 million for Q3 2025 at Monopar Therapeutics, down from -$3.2 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$1.6 million in Q3 2024 to a low of -$4.1 million in Q3 2025.
  • The 5-year median for Operating Income is -$2.5 million (2022), against an average of -$2.5 million.
  • Across the five-year window, Operating Income surged 31.75% in 2024 and plunged 159.89% in 2025, its largest moves.
  • Monopar Therapeutics' Operating Income stood at -$2.7 million in 2021, then dropped by 8.5% to -$2.9 million in 2022, then advanced by 28.98% to -$2.1 million in 2023, then advanced by 23.77% to -$1.6 million in 2024, then slumped by 159.89% to -$4.1 million in 2025.
  • The last three Operating Income figures came in at -$4.1 million (Q3 2025), -$3.2 million (Q2 2025), and -$3.2 million (Q1 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -2.97 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -15.76 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 Monopar Therapeutics 441.25 Mn 441.25 Mn - -

Historic Data

Download Data
DateValue
Sep 30, 2025 -4.09 Mn
Jun 30, 2025 -3.23 Mn
Mar 31, 2025 -3.22 Mn
Sep 30, 2024 -1.57 Mn
Jun 30, 2024 -1.79 Mn
Mar 31, 2024 -1.72 Mn
Sep 30, 2023 -2.07 Mn
Jun 30, 2023 -2.33 Mn
Mar 31, 2023 -2.53 Mn
Dec 31, 2022 -2.91 Mn
Sep 30, 2022 -2.41 Mn
Jun 30, 2022 -2.76 Mn
Mar 31, 2022 -2.46 Mn
Dec 31, 2021 -2.68 Mn
Sep 30, 2021 -2.46 Mn
Jun 30, 2021 -2.09 Mn
Mar 31, 2021 -1.89 Mn
Dec 31, 2020 -2.26 Mn
Sep 30, 2020 -1.65 Mn
Jun 30, 2020 -1.46 Mn