Mineralys Therapeutics (MLYS) Operating Income (2022 - 2026)

Mineralys Therapeutics (MLYS) reported Operating Income of -$45.3 million for Q1 2026, down 2.01% on a YoY basis from -$46.3 million in Q1 2025, and down 18.44% sequentially from -$38.3 million in Q4 2025.

Mineralys Therapeutics (MLYS) Operating Income (2022 - 2026) Analysis & Trends

Mineralys Therapeutics (MLYS) has 5 years of Operating Income data on file, last reported at -$45.3 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income fell 2.01% year-over-year to -$45.3 million; the trailing twelve-month figure through Mar 2026 stood at -$171.5 million (up 14.88% YoY), and the FY2025 full-year result was -$170.6 million, up 11.33% from the prior year.
  • Operating Income slipped to -$45.3 million in Q1 2026, from -$38.3 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$6.5 million in Q2 2022 to a low of -$60.1 million in Q3 2024.
  • A 5-year average of -$30.9 million and a median of -$35.4 million in 2024 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income tumbled 253.94% in 2023 and surged 31.57% in 2025, its largest moves.
  • Tracing MLYS's Operating Income over 5 years: stood at -$10.0 million in 2022, then slumped by 176.89% to -$27.7 million in 2023, then sank by 86.81% to -$51.8 million in 2024, then climbed by 26.05% to -$38.3 million in 2025, then decreased by 18.44% to -$45.3 million in 2026.
  • Business Quant data shows MLYS's Operating Income at -$45.3 million in Q1 2026, -$38.3 million in Q4 2025, and -$41.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Mineralys Therapeutics 2.21 Bn 2.21 Bn - -45.34 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -45.34 Mn
Dec 31, 2025 -38.28 Mn
Sep 30, 2025 -41.13 Mn
Jun 30, 2025 -46.75 Mn
Mar 31, 2025 -44.45 Mn
Dec 31, 2024 -51.77 Mn
Sep 30, 2024 -60.11 Mn
Jun 30, 2024 -45.17 Mn
Mar 31, 2024 -35.36 Mn
Dec 31, 2023 -27.71 Mn
Sep 30, 2023 -26.27 Mn
Jun 30, 2023 -15.74 Mn
Mar 31, 2023 -14.94 Mn
Dec 31, 2022 -10.01 Mn
Sep 30, 2022 -7.42 Mn
Jun 30, 2022 -6.48 Mn
Mar 31, 2022 -7.57 Mn