Mineralys Therapeutics (MLYS) EBITDA (2022 - 2026)
Quarterly results put EBITDA at -$45.3 million for Q1 2026, down 2.01% from a year ago — trailing twelve months through Mar 2026 was -$171.5 million (up 14.88% YoY), and the annual figure for FY2025 was -$170.6 million, up 11.33%.
Mineralys Therapeutics has reported EBITDA over the past 5 years, most recently at -$45.3 million for Q1 2026.
- EBITDA reached -$45.3 million in Q1 2026 per MLYS's latest filing, down from -$38.3 million in the prior quarter.
- Across five years, EBITDA topped out at -$6.5 million in Q2 2022 and bottomed at -$60.1 million in Q3 2024.
- Median EBITDA over the past 5 years was -$35.4 million (2024), compared with a mean of -$30.9 million.
- The largest annual shift saw EBITDA crashed 253.94% in 2023 before it surged 31.57% in 2025.
- Over 5 years, EBITDA stood at -$10.0 million in 2022, then crashed by 176.89% to -$27.7 million in 2023, then plummeted by 86.81% to -$51.8 million in 2024, then grew by 26.05% to -$38.3 million in 2025, then fell by 18.44% to -$45.3 million in 2026.
- Business Quant data shows EBITDA for MLYS at -$45.3 million in Q1 2026, -$38.3 million in Q4 2025, and -$41.1 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | -13.63 Mn |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | -14.44 Mn |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 661.60 Mn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | -3.82 Mn |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 201.19 Mn |
| 10 | Mineralys Therapeutics | 2.50 Bn | 2.50 Bn | - | -45.34 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -45.34 Mn |
| Dec 31, 2025 | -38.28 Mn |
| Sep 30, 2025 | -41.13 Mn |
| Jun 30, 2025 | -46.75 Mn |
| Mar 31, 2025 | -44.45 Mn |
| Dec 31, 2024 | -51.77 Mn |
| Sep 30, 2024 | -60.11 Mn |
| Jun 30, 2024 | -45.17 Mn |
| Mar 31, 2024 | -35.36 Mn |
| Dec 31, 2023 | -27.71 Mn |
| Sep 30, 2023 | -26.27 Mn |
| Jun 30, 2023 | -15.74 Mn |
| Mar 31, 2023 | -14.94 Mn |
| Dec 31, 2022 | -10.01 Mn |
| Sep 30, 2022 | -7.42 Mn |
| Jun 30, 2022 | -6.48 Mn |
| Mar 31, 2022 | -7.57 Mn |