Mineralys Therapeutics (MLYS) EBITDA (2022 - 2026)

Mineralys Therapeutics' (MLYS) quarterly EBITDA came in at -$45.3 million in Q1 2026, down 2.01% year-on-year from -$46.3 million in Q1 2025, and down 18.44% quarter-over-quarter from -$38.3 million in Q4 2025.

Mineralys Therapeutics (MLYS) EBITDA (2022 - 2026) Analysis & Trends

Mineralys Therapeutics has disclosed EBITDA across 5 years of filings, most recently posting -$45.3 million for Q1 2026.

  • EBITDA for Q1 2026 came in at -$45.3 million, down 2.01% year-over-year; the trailing twelve-month figure through Mar 2026 was -$171.5 million (up 14.88% YoY), and the FY2025 annual result was -$170.6 million, up 11.33% from the prior year.
  • EBITDA came in at -$45.3 million for Q1 2026 at Mineralys Therapeutics, down from -$38.3 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$6.5 million in Q2 2022 to a low of -$60.1 million in Q3 2024.
  • The 5-year median for EBITDA is -$35.4 million (2024), against an average of -$30.9 million.
  • Across the five-year window, EBITDA sank 253.94% in 2023 and surged 31.57% in 2025, its largest moves.
  • Mineralys Therapeutics' EBITDA stood at -$10.0 million in 2022, then sank by 176.89% to -$27.7 million in 2023, then plunged by 86.81% to -$51.8 million in 2024, then grew by 26.05% to -$38.3 million in 2025, then slipped by 18.44% to -$45.3 million in 2026.
  • The last three EBITDA figures came in at -$45.3 million (Q1 2026), -$38.3 million (Q4 2025), and -$41.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -13.63 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -14.44 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -752,618.00
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 Mineralys Therapeutics 1.95 Bn 1.95 Bn - -45.34 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -45.34 Mn
Dec 31, 2025 -38.28 Mn
Sep 30, 2025 -41.13 Mn
Jun 30, 2025 -46.75 Mn
Mar 31, 2025 -44.45 Mn
Dec 31, 2024 -51.77 Mn
Sep 30, 2024 -60.11 Mn
Jun 30, 2024 -45.17 Mn
Mar 31, 2024 -35.36 Mn
Dec 31, 2023 -27.71 Mn
Sep 30, 2023 -26.27 Mn
Jun 30, 2023 -15.74 Mn
Mar 31, 2023 -14.94 Mn
Dec 31, 2022 -10.01 Mn
Sep 30, 2022 -7.42 Mn
Jun 30, 2022 -6.48 Mn
Mar 31, 2022 -7.57 Mn