Mineralys Therapeutics (MLYS) EBITDA (2022 - 2026)
Mineralys Therapeutics' (MLYS) quarterly EBITDA came in at -$45.3 million in Q1 2026, down 2.01% year-on-year from -$46.3 million in Q1 2025, and down 18.44% quarter-over-quarter from -$38.3 million in Q4 2025.
Mineralys Therapeutics (MLYS) EBITDA (2022 - 2026) Analysis & Trends
Mineralys Therapeutics has disclosed EBITDA across 5 years of filings, most recently posting -$45.3 million for Q1 2026.
- EBITDA for Q1 2026 came in at -$45.3 million, down 2.01% year-over-year; the trailing twelve-month figure through Mar 2026 was -$171.5 million (up 14.88% YoY), and the FY2025 annual result was -$170.6 million, up 11.33% from the prior year.
- EBITDA came in at -$45.3 million for Q1 2026 at Mineralys Therapeutics, down from -$38.3 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$6.5 million in Q2 2022 to a low of -$60.1 million in Q3 2024.
- The 5-year median for EBITDA is -$35.4 million (2024), against an average of -$30.9 million.
- Across the five-year window, EBITDA sank 253.94% in 2023 and surged 31.57% in 2025, its largest moves.
- Mineralys Therapeutics' EBITDA stood at -$10.0 million in 2022, then sank by 176.89% to -$27.7 million in 2023, then plunged by 86.81% to -$51.8 million in 2024, then grew by 26.05% to -$38.3 million in 2025, then slipped by 18.44% to -$45.3 million in 2026.
- The last three EBITDA figures came in at -$45.3 million (Q1 2026), -$38.3 million (Q4 2025), and -$41.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -65.83 Mn |
| 10 | Mineralys Therapeutics | 1.95 Bn | 1.95 Bn | - | -45.34 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -45.34 Mn |
| Dec 31, 2025 | -38.28 Mn |
| Sep 30, 2025 | -41.13 Mn |
| Jun 30, 2025 | -46.75 Mn |
| Mar 31, 2025 | -44.45 Mn |
| Dec 31, 2024 | -51.77 Mn |
| Sep 30, 2024 | -60.11 Mn |
| Jun 30, 2024 | -45.17 Mn |
| Mar 31, 2024 | -35.36 Mn |
| Dec 31, 2023 | -27.71 Mn |
| Sep 30, 2023 | -26.27 Mn |
| Jun 30, 2023 | -15.74 Mn |
| Mar 31, 2023 | -14.94 Mn |
| Dec 31, 2022 | -10.01 Mn |
| Sep 30, 2022 | -7.42 Mn |
| Jun 30, 2022 | -6.48 Mn |
| Mar 31, 2022 | -7.57 Mn |