Mirum Pharmaceuticals (MIRM) EBITDA Margin (2021 - 2026)
Mirum Pharmaceuticals (MIRM) posted EBITDA Margin of -28.00% for Q3 2026, down 34.85 percentage points from 6.85% a year earlier and down 8.18 percentage points from the prior quarter.
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Mirum Pharmaceuticals (MIRM) EBITDA Margin (2021 - 2026) Analysis & Trends
For the trailing twelve months through Sep 30, 2026, EBITDA Margin at Mirum Pharmaceuticals was -129.27%, down 125.92 percentage points year-over-year; for FY2025, it came in at 0.74%, up 19.24 percentage points from FY2024.
- Annual EBITDA Margin has increased for four consecutive years, with a four-year change of +903.75 percentage points (FY2021 to FY2025).
- In prior years, Mirum Pharmaceuticals' EBITDA Margin was -18.50% in FY2024 (+33.66 pp), -52.16% in FY2023 (+113.92 pp), -166.08% in FY2022 (+736.93 pp) and -903.01% in FY2021.
- Quarterly EBITDA Margin has run from a low of -1441.46% in Q4 2021 to a high of 6.85% in Q3 2025 over five years.
- On a year-over-year basis, EBITDA Margin has declined in each of the last three quarters, with an average year-over-year change of -54.74 percentage points over the last eight quarters.
- The strongest year-over-year quarter for EBITDA Margin in the past five years was Q4 2022, with a gain of 1323.35 percentage points; the weakest was Q1 2026, with a drop of 481.40 percentage points.
- According to Business Quant data, EBITDA Margin for the three prior quarters was -19.83% (Q2 2026), -489.20% (Q1 2026) and 1.30% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,264.65 Bn | 1,238.27 Bn | 20.46 Bn | 54.65% |
| 2 | Johnson & Johnson | 677.74 Bn | 597.60 Bn | 17.30 Bn | 32.68% |
| 3 | AbbVie | 517.10 Bn | 485.11 Bn | 13.12 Bn | 46.88% |
| 4 | Merck | 362.23 Bn | 325.17 Bn | 13.19 Bn | 40.75% |
| 5 | Novartis Ag | 315.90 Bn | 276.16 Bn | 11.24 Bn | - |
| 6 | Astrazeneca | 289.40 Bn | 266.24 Bn | 12.86 Bn | - |
| 7 | Amgen | 249.90 Bn | 201.56 Bn | 7.58 Bn | 46.62% |
| 8 | Gilead Sciences | 209.15 Bn | 184.26 Bn | 6.73 Bn | 50.63% |
| 9 | Pfizer | 165.88 Bn | 113.23 Bn | 12.56 Bn | 42.49% |
| 10 | Mirum Pharmaceuticals | 6.06 Bn | 4.48 Bn | 150.55 Mn | -28.00% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -28.00% |
| Jun 30, 2026 | -19.83% |
| Mar 31, 2026 | -489.20% |
| Dec 31, 2025 | 1.30% |
| Sep 30, 2025 | 6.85% |
| Jun 30, 2025 | 1.17% |
| Mar 31, 2025 | -7.79% |
| Dec 31, 2024 | -17.85% |
| Sep 30, 2024 | -6.87% |
| Jun 30, 2024 | -23.08% |
| Mar 31, 2024 | -29.46% |
| Dec 31, 2023 | -38.38% |
| Sep 30, 2023 | -46.25% |
| Jun 30, 2023 | -60.35% |
| Mar 31, 2023 | -81.69% |
| Dec 31, 2022 | -118.11% |
| Sep 30, 2022 | -169.25% |
| Jun 30, 2022 | -176.40% |
| Mar 31, 2022 | -251.27% |
| Dec 31, 2021 | -1,441.46% |
API Access
Mirum Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=MIRM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "MIRM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=MIRM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();