Growth Metrics

Mirum Pharmaceuticals (MIRM) EBITDA (2019 - 2026)

Mirum Pharmaceuticals' quarterly EBITDA came in at -$789.5 million in Q1 2026, down 5099.66% year-on-year from $15.8 million in Q1 2025, and down 17186.29% quarter-over-quarter from -$4.6 million in Q4 2025.

Mirum Pharmaceuticals has reported EBITDA for 8 years, with the latest figure at -$789.5 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 5099.66% year-over-year to -$789.5 million; the trailing twelve-month figure through Mar 2026 stood at -$796.4 million (down 943.51% YoY), and the FY2025 full-year result was -$22.1 million, up 74.73% from the prior year.
  • EBITDA for Q1 2026 stood at -$789.5 million, down from -$4.6 million in the prior quarter.
  • The five-year high for EBITDA was $2.6 million in Q3 2025, with the low at -$789.5 million in Q1 2026.
  • Average EBITDA over 5 years is -$67.0 million, with a median of -$25.1 million recorded in 2023.
  • Year-over-year, EBITDA surged 120.52% in 2025 and slumped 5099.66% in 2026.
  • Tracing MIRM's EBITDA over 5 years: stood at -$34.2 million in 2022, then rose by 4.61% to -$32.6 million in 2023, then climbed by 25.67% to -$24.2 million in 2024, then jumped by 81.15% to -$4.6 million in 2025, then tumbled by 17186.29% to -$789.5 million in 2026.
  • The last three EBITDA figures came in at -$789.5 million (Q1 2026), -$4.6 million (Q4 2025), and $2.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 Mirum Pharmaceuticals 5.97 Bn 5.59 Bn 131.08 Mn -789.47 Mn

Historic Data

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DateValue
Mar 31, 2026 -789.47 Mn
Dec 31, 2025 -4.57 Mn
Sep 30, 2025 2.60 Mn
Jun 30, 2025 -4.99 Mn
Mar 31, 2025 -15.18 Mn
Dec 31, 2024 -24.22 Mn
Sep 30, 2024 -12.68 Mn
Jun 30, 2024 -24.23 Mn
Mar 31, 2024 -26.47 Mn
Dec 31, 2023 -32.59 Mn
Sep 30, 2023 -25.15 Mn
Jun 30, 2023 -24.27 Mn
Mar 31, 2023 -27.15 Mn
Dec 31, 2022 -34.16 Mn
Sep 30, 2022 -32.88 Mn
Jun 30, 2022 -31.44 Mn
Mar 31, 2022 -32.74 Mn
Dec 31, 2021 -45.58 Mn
Sep 30, 2021 -42.82 Mn
Jun 30, 2021 -37.40 Mn
Mar 31, 2021 -47.61 Mn
Dec 31, 2020 -36.95 Mn
Sep 30, 2020 -21.72 Mn
Jun 30, 2020 -23.60 Mn
Mar 31, 2020 -22.03 Mn
Dec 31, 2019 -18.66 Mn
Sep 30, 2019 -15.02 Mn
Jun 30, 2019 -13.53 Mn
Mar 31, 2019 -6.18 Mn