Mirum Pharmaceuticals (MIRM) EBIT Margin (2021 - 2026)
Mirum Pharmaceuticals' EBIT Margin came in at -32.17% for Q3 2026, down 34.13 percentage points from 1.96% a year earlier and down 8.03 percentage points from the prior quarter.
Mirum Pharmaceuticals (MIRM) EBIT Margin (2021 - 2026) Analysis & Trends
Over the trailing twelve months to Sep 30, 2026, Mirum Pharmaceuticals reported EBIT Margin of -133.62%, down 124.77 percentage points year-over-year; for FY2025, it came in at -4.25%, up 21.76 percentage points from FY2024.
- EBIT Margin has increased in each of the last four years, with a four-year change of +901.87 percentage points (FY2021 to FY2025).
- Going back by year, EBIT Margin was -26.00% in FY2024 (+32.56 pp), -58.57% in FY2023 (+111.71 pp), -170.28% in FY2022 (+735.84 pp) and -906.12% in FY2021.
- The five-year range for quarterly EBIT Margin is -1452.36% (Q4 2021) to 1.96% (Q3 2025).
- Year-over-year, EBIT Margin has declined for three consecutive quarters, with an average year-over-year change of -52.86 percentage points over the last eight quarters.
- The fastest year-over-year change in EBIT Margin over five years came in Q4 2022 (a gain of 1329.94 percentage points), and the weakest in Q1 2026 (a drop of 480.17 percentage points).
- Business Quant data shows MIRM's EBIT Margin at -24.14% (Q2 2026), -493.78% (Q1 2026) and -3.07% (Q4 2025) in the three quarters before Q3 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,264.65 Bn | 1,238.27 Bn | 20.46 Bn | 52.42% |
| 2 | Johnson & Johnson | 677.74 Bn | 597.60 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 517.10 Bn | 485.11 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 362.23 Bn | 325.17 Bn | 13.19 Bn | 30.89% |
| 5 | Novartis Ag | 315.90 Bn | 276.16 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 289.40 Bn | 266.24 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 249.90 Bn | 201.56 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 209.15 Bn | 184.26 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 165.88 Bn | 113.23 Bn | 12.56 Bn | 32.98% |
| 10 | Mirum Pharmaceuticals | 6.06 Bn | 4.48 Bn | 150.55 Mn | -32.17% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -32.17% |
| Jun 30, 2026 | -24.14% |
| Mar 31, 2026 | -493.78% |
| Dec 31, 2025 | -3.07% |
| Sep 30, 2025 | 1.96% |
| Jun 30, 2025 | -3.90% |
| Mar 31, 2025 | -13.61% |
| Dec 31, 2024 | -24.36% |
| Sep 30, 2024 | -14.03% |
| Jun 30, 2024 | -31.12% |
| Mar 31, 2024 | -38.24% |
| Dec 31, 2023 | -46.85% |
| Sep 30, 2023 | -52.69% |
| Jun 30, 2023 | -64.73% |
| Mar 31, 2023 | -85.92% |
| Dec 31, 2022 | -122.41% |
| Sep 30, 2022 | -175.09% |
| Jun 30, 2022 | -179.83% |
| Mar 31, 2022 | -253.92% |
| Dec 31, 2021 | -1,452.36% |
Mirum Pharmaceuticals EBIT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebit-margin&ticker=MIRM&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebit-margin", "ticker": "MIRM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebit-margin&ticker=MIRM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();