Macrogenics (MGNX) Operating Income (2012 - 2026)

Macrogenics (MGNX) reported Operating Income of -$33.4 million for Q1 2026, up 21.55% year-over-year from -$27.5 million in Q1 2025, and down 176.42% quarter-over-quarter from -$12.1 million in Q4 2025.

Macrogenics (MGNX) Operating Income (2012 - 2026) Analysis & Trends

Macrogenics (MGNX) has 15 years of Operating Income data on file, last reported at -$33.4 million in Q1 2026.

  • Operating Income for Q1 2026 came in at -$33.4 million, up 21.55% year-over-year; the trailing twelve-month figure through Mar 2026 was -$63.7 million (up 35.99% YoY), and the FY2025 annual result was -$72.8 million, up 34.13% from the prior year.
  • Operating Income fell to -$33.4 million in Q1 2026 per MGNX's latest filing, from -$12.1 million in the prior quarter.
  • Over five years, Operating Income peaked at $54.2 million in Q3 2024 and troughed at -$66.6 million in Q1 2022.
  • A 5-year average of -$29.8 million and a median of -$38.4 million in 2023 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2023 and 2024: Operating Income plunged 511.87% in 2023, then soared 252.64% in 2024.
  • A 5-year view of Operating Income shows it stood at $12.0 million in 2022, then sank by 511.87% to -$49.4 million in 2023, then decreased by 7.06% to -$52.8 million in 2024, then soared by 77.11% to -$12.1 million in 2025, then sank by 176.42% to -$33.4 million in 2026.
  • Business Quant data shows MGNX's Operating Income at -$33.4 million in Q1 2026, -$12.1 million in Q4 2025, and $18.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Macrogenics 260.14 Mn 193.63 Mn - -33.44 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -33.44 Mn
Dec 31, 2025 -12.10 Mn
Sep 30, 2025 18.64 Mn
Jun 30, 2025 -36.76 Mn
Mar 31, 2025 -42.62 Mn
Dec 31, 2024 -52.84 Mn
Sep 30, 2024 54.19 Mn
Jun 30, 2024 -58.18 Mn
Mar 31, 2024 -53.75 Mn
Dec 31, 2023 -49.35 Mn
Sep 30, 2023 -35.50 Mn
Jun 30, 2023 -44.96 Mn
Mar 31, 2023 -38.43 Mn
Dec 31, 2022 11.98 Mn
Sep 30, 2022 -24.96 Mn
Jun 30, 2022 -41.81 Mn
Mar 31, 2022 -66.64 Mn
Dec 31, 2021 -58.24 Mn
Sep 30, 2021 -52.99 Mn
Jun 30, 2021 -40.28 Mn