Madrigal Pharmaceuticals MDGL
NASDAQ MDGL
$547.73 +5.12 (+0.94%)
As of: Sep 4, 2026 · 12:47 PM EDT

Madrigal Pharmaceuticals (MDGL) Profit After Tax (2010 - 2026)

Madrigal Pharmaceuticals (MDGL) posted quarterly Profit After Tax of -$57.9 million for Q2 2026, down 37.03% year-over-year from -$92.0 million in Q2 2025, and up 38.62% quarter-over-quarter from -$94.4 million in Q1 2026.

Analysis

Madrigal Pharmaceuticals (MDGL) Profit After Tax (2010 - 2026) Analysis & Trends

Madrigal Pharmaceuticals (MDGL) has reported Profit After Tax for 17 consecutive years, with -$57.9 million the latest figure, recorded in Q2 2026.

  • In Q2 2026, Profit After Tax fell 37.03% year-over-year to -$57.9 million; the TTM figure through Jun 2026 stood at -$325.1 million (down 15.33% YoY), while the FY2025 annual figure was -$288.3 million, up 38.12% from the prior year.
  • Profit After Tax advanced to -$57.9 million in Q2 2026 per MDGL's latest filing, from -$94.4 million in the prior quarter.
  • Across five years, Profit After Tax topped out at -$42.3 million in Q2 2025 and bottomed at -$152.0 million in Q2 2024.
  • Historically, Profit After Tax has averaged -$87.5 million across 5 years, with a median of -$83.5 million in 2022.
  • Annual changes were most pronounced in 2024 — Profit After Tax sank 91.87% — and 2025, when it soared 72.18%.
  • Madrigal Pharmaceuticals' Profit After Tax stood at -$85.9 million in 2022, then sank by 30.6% to -$112.2 million in 2023, then soared by 47.04% to -$59.4 million in 2024, then climbed by 1.39% to -$58.6 million in 2025, then increased by 1.11% to -$57.9 million in 2026.
  • Business Quant data shows MDGL's Profit After Tax at -$57.9 million in Q2 2026, -$94.4 million in Q1 2026, and -$58.6 million in Q4 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 139.62 Bn 131.77 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.73 Bn 77.73 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 63.53 Bn 58.35 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.23 Bn 53.09 Bn 52.00 Mn -782.00 Mn
5 Revolution Medicines 44.05 Bn 44.05 Bn - -644.37 Mn
6 BeOne Medicines 40.03 Bn 34.93 Bn 1.53 Bn 237.01 Mn
7 Alnylam Pharmaceuticals 35.50 Bn 32.19 Bn 992.69 Mn 164.49 Mn
8 Royalty Pharma 28.52 Bn 27.68 Bn - 81.49 Mn
9 Insmed 27.46 Bn 26.30 Bn 358.27 Mn -16.62 Mn
10 Madrigal Pharmaceuticals 15.96 Bn 15.12 Bn - -57.94 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -57.94 Mn
Mar 31, 2026 -94.39 Mn
Dec 31, 2025 -58.59 Mn
Sep 30, 2025 -114.19 Mn
Jun 30, 2025 -42.28 Mn
Mar 31, 2025 -73.24 Mn
Dec 31, 2024 -59.42 Mn
Sep 30, 2024 -106.96 Mn
Jun 30, 2024 -151.97 Mn
Mar 31, 2024 -147.54 Mn
Dec 31, 2023 -112.19 Mn
Sep 30, 2023 -98.74 Mn
Jun 30, 2023 -85.80 Mn
Mar 31, 2023 -76.90 Mn
Dec 31, 2022 -85.91 Mn
Sep 30, 2022 -81.20 Mn
Jun 30, 2022 -70.73 Mn
Mar 31, 2022 -57.52 Mn
Dec 31, 2021 -64.55 Mn
Sep 30, 2021 -63.10 Mn