Madrigal Pharmaceuticals (MDGL) Operating Income (2010 - 2026)
Madrigal Pharmaceuticals' (MDGL) quarterly Operating Income came in at -$92.7 million in Q1 2026, down 16.91% year-on-year from -$111.6 million in Q1 2025, and down 55.55% on a QoQ basis from -$59.6 million in Q4 2025.
Madrigal Pharmaceuticals (MDGL) Operating Income (2010 - 2026) Analysis & Trends
Madrigal Pharmaceuticals (MDGL) has 17 years of Operating Income data on file, last reported at -$92.7 million in Q1 2026.
- On a quarterly basis, Operating Income fell 16.91% year-over-year to -$92.7 million in Q1 2026; TTM through Mar 2026 was -$313.5 million, a 26.26% increase from a year earlier, with the FY2025 full-year figure at -$300.1 million, up 39.72% from the prior year.
- Operating Income for Q1 2026 stood at -$92.7 million, down from -$59.6 million in the prior quarter.
- Over the last five years, Operating Income for MDGL reached as high as -$47.2 million in Q2 2025 and fell as low as -$162.5 million in Q2 2024.
- Historically, Operating Income has averaged -$92.0 million across 5 years, with a median of -$85.3 million in 2022.
- Across the five-year window, Operating Income slumped 94.08% in 2024 and soared 70.96% in 2025, its largest moves.
- Year by year, Operating Income stood at -$85.3 million in 2022, then tumbled by 37.37% to -$117.2 million in 2023, then surged by 42.82% to -$67.0 million in 2024, then climbed by 11.03% to -$59.6 million in 2025, then tumbled by 55.55% to -$92.7 million in 2026.
- Per Business Quant data, the three most recent Operating Income figures were -$92.7 million in Q1 2026, -$59.6 million in Q4 2025, and -$114.0 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 249.90 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -3.72 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 493.00 Mn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -445.22 Mn |
| 10 | Madrigal Pharmaceuticals | 15.77 Bn | 15.54 Bn | - | -92.72 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -92.72 Mn |
| Dec 31, 2025 | -59.61 Mn |
| Sep 30, 2025 | -113.98 Mn |
| Jun 30, 2025 | -47.20 Mn |
| Mar 31, 2025 | -79.31 Mn |
| Dec 31, 2024 | -67.00 Mn |
| Sep 30, 2024 | -116.30 Mn |
| Jun 30, 2024 | -162.54 Mn |
| Mar 31, 2024 | -152.04 Mn |
| Dec 31, 2023 | -117.18 Mn |
| Sep 30, 2023 | -98.53 Mn |
| Jun 30, 2023 | -86.45 Mn |
| Mar 31, 2023 | -78.34 Mn |
| Dec 31, 2022 | -85.30 Mn |
| Sep 30, 2022 | -80.41 Mn |
| Jun 30, 2022 | -70.27 Mn |
| Mar 31, 2022 | -57.59 Mn |
| Dec 31, 2021 | -64.60 Mn |
| Sep 30, 2021 | -63.16 Mn |
| Jun 30, 2021 | -61.74 Mn |