Madrigal Pharmaceuticals (MDGL) EBIT (2010 - 2026)

Madrigal Pharmaceuticals (MDGL) posted quarterly EBIT of -$56.3 million for Q2 2026, down 19.29% year-over-year from -$69.8 million in Q2 2025, and up 39.27% quarter-over-quarter from -$92.7 million in Q1 2026.

Madrigal Pharmaceuticals (MDGL) EBIT (2010 - 2026) Analysis & Trends

Madrigal Pharmaceuticals (MDGL) has reported EBIT for 17 consecutive years, with -$56.3 million the latest figure, recorded in Q2 2026.

  • In Q2 2026, EBIT fell 19.29% year-over-year to -$56.3 million; the TTM figure through Jun 2026 stood at -$322.6 million (down 4.13% YoY), while the FY2025 annual figure was -$300.1 million, up 39.72% from the prior year.
  • EBIT rose to -$56.3 million in Q2 2026 per MDGL's latest filing, from -$92.7 million in the prior quarter.
  • Across five years, EBIT topped out at -$47.2 million in Q2 2025 and bottomed at -$162.5 million in Q2 2024.
  • Historically, EBIT has averaged -$90.1 million across 5 years, with a median of -$82.9 million in 2022.
  • Annual changes were most pronounced in 2024 — EBIT plunged 94.08% — and 2025, when it surged 70.96%.
  • Madrigal Pharmaceuticals' EBIT stood at -$85.3 million in 2022, then tumbled by 37.37% to -$117.2 million in 2023, then soared by 42.82% to -$67.0 million in 2024, then gained by 11.03% to -$59.6 million in 2025, then grew by 5.54% to -$56.3 million in 2026.
  • Business Quant data shows MDGL's EBIT at -$56.3 million in Q2 2026, -$92.7 million in Q1 2026, and -$59.6 million in Q4 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Madrigal Pharmaceuticals 14.79 Bn 13.95 Bn - -56.31 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -56.31 Mn
Mar 31, 2026 -92.72 Mn
Dec 31, 2025 -59.61 Mn
Sep 30, 2025 -113.98 Mn
Jun 30, 2025 -47.20 Mn
Mar 31, 2025 -79.31 Mn
Dec 31, 2024 -67.00 Mn
Sep 30, 2024 -116.30 Mn
Jun 30, 2024 -162.54 Mn
Mar 31, 2024 -152.04 Mn
Dec 31, 2023 -117.18 Mn
Sep 30, 2023 -98.53 Mn
Jun 30, 2023 -86.45 Mn
Mar 31, 2023 -78.34 Mn
Dec 31, 2022 -85.30 Mn
Sep 30, 2022 -80.41 Mn
Jun 30, 2022 -70.27 Mn
Mar 31, 2022 -57.59 Mn
Dec 31, 2021 -64.60 Mn
Sep 30, 2021 -63.16 Mn