MBX Biosciences (MBX) Operating Income (2023 - 2026)

MBX Biosciences' (MBX) quarterly Operating Income came in at -$27.3 million in Q1 2026, down 2.77% year-on-year from -$28.0 million in Q1 2025, and down 5.7% quarter-over-quarter from -$25.8 million in Q4 2025.

MBX Biosciences (MBX) Operating Income (2023 - 2026) Analysis & Trends

MBX Biosciences has disclosed Operating Income across 4 years of filings, most recently posting -$27.3 million for Q1 2026.

  • Operating Income for Q1 2026 came in at -$27.3 million, down 2.77% year-over-year; the trailing twelve-month figure through Mar 2026 was -$98.8 million (down 21.35% YoY), and the FY2025 annual result was -$98.1 million, down 43.79% from the prior year.
  • Operating Income came in at -$27.3 million for Q1 2026 at MBX Biosciences, down from -$25.8 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$10.0 million in Q4 2023 to a low of -$27.3 million in Q1 2026.
  • The 4-year median for Operating Income is -$19.6 million (2024), against an average of -$19.5 million.
  • Across the five-year window, Operating Income tumbled 99.26% in 2025 and slipped 2.77% in 2026, its largest moves.
  • MBX Biosciences' Operating Income stood at -$10.0 million in 2023, then plunged by 86.27% to -$18.6 million in 2024, then plunged by 38.61% to -$25.8 million in 2025, then slipped by 5.7% to -$27.3 million in 2026.
  • The last three Operating Income figures came in at -$27.3 million (Q1 2026), -$25.8 million (Q4 2025), and -$23.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - -
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - -2.97 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - -15.76 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.82 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - -
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.71 Bn 91.71 Bn - -65.83 Mn
10 MBX Biosciences 1.44 Bn 1.44 Bn - -27.27 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -27.27 Mn
Dec 31, 2025 -25.80 Mn
Sep 30, 2025 -23.93 Mn
Jun 30, 2025 -21.81 Mn
Mar 31, 2025 -26.53 Mn
Dec 31, 2024 -18.61 Mn
Sep 30, 2024 -19.61 Mn
Jun 30, 2024 -16.66 Mn
Mar 31, 2024 -13.31 Mn
Dec 31, 2023 -9.99 Mn
Sep 30, 2023 -10.95 Mn