MBX Biosciences (MBX) Operating Income (2023 - 2026)

MBX Biosciences (MBX) posted Operating Income of -$27.3 million for Q1 2026, down 5.7% sequentially from -$25.8 million in Q4 2025, and down 2.77% YoY from -$28.0 million in Q1 2025.

MBX Biosciences (MBX) Operating Income (2023 - 2026) Analysis & Trends

MBX Biosciences has reported Operating Income for 4 years, with the latest figure at -$27.3 million in Q1 2026.

  • Quarterly Operating Income fell 2.77% year-over-year to -$27.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$98.8 million (down 21.35% YoY) and the FY2025 annual result came in at -$98.1 million, down 43.79% from the prior year.
  • Operating Income declined to -$27.3 million in Q1 2026 per MBX's latest filing, from -$25.8 million in the prior quarter.
  • Over five years, Operating Income peaked at -$10.0 million in Q4 2023 and troughed at -$27.3 million in Q1 2026.
  • A 4-year average of -$19.5 million and a median of -$19.6 million in 2024 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2025 and 2026: Operating Income tumbled 99.26% in 2025, then declined 2.77% in 2026.
  • Over 4 years, Operating Income stood at -$10.0 million in 2023, then plunged by 86.27% to -$18.6 million in 2024, then plunged by 38.61% to -$25.8 million in 2025, then declined by 5.7% to -$27.3 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$27.3 million, -$25.8 million, and -$23.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 MBX Biosciences 3.29 Bn 3.29 Bn - -40.93 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -40.93 Mn
Mar 31, 2026 -27.27 Mn
Dec 31, 2025 -25.80 Mn
Sep 30, 2025 -23.93 Mn
Jun 30, 2025 -21.81 Mn
Mar 31, 2025 -26.53 Mn
Dec 31, 2024 -18.61 Mn
Sep 30, 2024 -19.61 Mn
Jun 30, 2024 -16.66 Mn
Mar 31, 2024 -13.31 Mn
Dec 31, 2023 -9.99 Mn
Sep 30, 2023 -10.95 Mn