Maze Therapeutics (MAZE) Operating Income (2024 - 2026)

Maze Therapeutics' (MAZE) quarterly Operating Income came in at -$26.6 million in Q1 2026, up 24.99% year-on-year from -$21.2 million in Q1 2025, and up 30.23% quarter-over-quarter from -$38.1 million in Q4 2025.

Maze Therapeutics (MAZE) Operating Income (2024 - 2026) Analysis & Trends

Maze Therapeutics has disclosed Operating Income across 3 years of filings, most recently posting -$26.6 million for Q1 2026.

  • Operating Income for Q1 2026 came in at -$26.6 million, up 24.99% year-over-year; the trailing twelve-month figure through Mar 2026 was -$134.1 million (down 3601.85% YoY), and the FY2025 annual result was -$142.9 million, down 1374.18% from the prior year.
  • Operating Income came in at -$26.6 million for Q1 2026 at Maze Therapeutics, up from -$38.1 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $139.6 million in Q2 2024 to a low of -$76.1 million in Q4 2024.
  • The 3-year median for Operating Income is -$33.0 million (2025), against an average of -$17.6 million.
  • Peak annual rise in Operating Income reached 49.99% in 2025, while the deepest fall reached 126.14% in 2025.
  • Maze Therapeutics' Operating Income stood at -$76.1 million in 2024, then soared by 49.99% to -$38.1 million in 2025, then jumped by 30.23% to -$26.6 million in 2026.
  • The last three Operating Income figures came in at -$26.6 million (Q1 2026), -$38.1 million (Q4 2025), and -$33.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -2.97 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -19.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -15.76 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -3.82 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.14 Bn
9 Abivax 90.15 Bn 90.15 Bn - -65.83 Mn
10 Maze Therapeutics 1.31 Bn 1.31 Bn 18.21 Mn -26.55 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -26.55 Mn
Dec 31, 2025 -38.06 Mn
Sep 30, 2025 -32.97 Mn
Jun 30, 2025 -36.47 Mn
Mar 31, 2025 -35.40 Mn
Dec 31, 2024 -76.10 Mn
Sep 30, 2024 -24.23 Mn
Jun 30, 2024 139.56 Mn
Mar 31, 2024 -28.01 Mn