Maze Therapeutics (MAZE) EBITDA (2024 - 2026)

Maze Therapeutics recorded quarterly EBITDA of -$26.6 million in Q1 2026, up 30.23% quarter-over-quarter from -$38.1 million in Q4 2025, and up 24.99% year-over-year from -$21.2 million in Q1 2025.

Maze Therapeutics' EBITDA history runs 3 years deep, the most recent figure standing at -$26.6 million for Q1 2026.

  • In Q1 2026, EBITDA rose 24.99% year-over-year to -$26.6 million; the TTM figure through Mar 2026 stood at -$134.1 million (down 3601.85% YoY), while the FY2025 annual figure was -$142.9 million, down 1374.18% from the prior year.
  • EBITDA came in at -$26.6 million for Q1 2026 at Maze Therapeutics, up from -$38.1 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $139.6 million in Q2 2024 to a low of -$76.1 million in Q4 2024.
  • A 3-year average of -$17.6 million and a median of -$33.0 million in 2025 frame the typical range for EBITDA.
  • On a YoY basis, EBITDA climbed as much as 49.99% in 2025 and fell as far as 126.14% in 2025.
  • Maze Therapeutics' EBITDA stood at -$76.1 million in 2024, then jumped by 49.99% to -$38.1 million in 2025, then surged by 30.23% to -$26.6 million in 2026.
  • According to Business Quant data, EBITDA over the past three periods registered -$26.6 million, -$38.1 million, and -$33.0 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Maze Therapeutics 1.37 Bn 1.37 Bn 18.21 Mn -26.55 Mn

Historic Data

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DateValue
Mar 31, 2026 -26.55 Mn
Dec 31, 2025 -38.06 Mn
Sep 30, 2025 -32.97 Mn
Jun 30, 2025 -36.47 Mn
Mar 31, 2025 -35.40 Mn
Dec 31, 2024 -76.10 Mn
Sep 30, 2024 -24.23 Mn
Jun 30, 2024 139.56 Mn
Mar 31, 2024 -28.01 Mn