Lexeo Therapeutics (LXEO) EBITDA (2022 - 2026)

Lexeo Therapeutics' (LXEO) quarterly EBITDA came in at -$20.5 million in Q1 2026, up 37.05% year-on-year from -$15.0 million in Q1 2025, and up 11.2% quarter-over-quarter from -$23.1 million in Q4 2025.

Lexeo Therapeutics (LXEO) EBITDA (2022 - 2026) Analysis & Trends

Lexeo Therapeutics has disclosed EBITDA across 5 years of filings, most recently posting -$20.5 million for Q1 2026.

  • EBITDA for Q1 2026 came in at -$20.5 million, up 37.05% year-over-year; the trailing twelve-month figure through Mar 2026 was -$91.4 million (down 230.09% YoY), and the FY2025 annual result was -$99.7 million, down 1.25% from the prior year.
  • EBITDA came in at -$20.5 million for Q1 2026 at Lexeo Therapeutics, up from -$23.1 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $57.7 million in Q4 2024 to a low of -$32.6 million in Q1 2025.
  • The 5-year median for EBITDA is -$20.5 million (2026), against an average of -$16.1 million.
  • Across the five-year window, EBITDA surged 485.42% in 2024 and sank 140.05% in 2025, its largest moves.
  • Lexeo Therapeutics' EBITDA stood at -$15.2 million in 2022, then gained by 1.47% to -$15.0 million in 2023, then soared by 485.42% to $57.7 million in 2024, then tumbled by 140.05% to -$23.1 million in 2025, then rose by 11.2% to -$20.5 million in 2026.
  • The last three EBITDA figures came in at -$20.5 million (Q1 2026), -$23.1 million (Q4 2025), and -$21.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Lexeo Therapeutics 405.92 Mn 212.88 Mn - -20.53 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -20.53 Mn
Dec 31, 2025 -23.12 Mn
Sep 30, 2025 -21.65 Mn
Jun 30, 2025 -26.06 Mn
Mar 31, 2025 -32.61 Mn
Dec 31, 2024 57.71 Mn
Sep 30, 2024 -31.54 Mn
Jun 30, 2024 -21.24 Mn
Mar 31, 2024 -21.68 Mn
Dec 31, 2023 -14.97 Mn
Sep 30, 2023 -20.27 Mn
Jun 30, 2023 -13.98 Mn
Mar 31, 2023 -19.29 Mn
Dec 31, 2022 -15.20 Mn
Sep 30, 2022 -17.48 Mn