Lexeo Therapeutics (LXEO) EBITDA (2022 - 2026)

Lexeo Therapeutics (LXEO) reported EBITDA of -$22.3 million for Q1 2026, up 33.94% on a YoY basis from -$16.7 million in Q1 2025, and up 3.39% sequentially from -$23.1 million in Q4 2025.

Lexeo Therapeutics (LXEO) EBITDA (2022 - 2026) Analysis & Trends

Lexeo Therapeutics (LXEO) has 5 years of EBITDA data on file, last reported at -$22.3 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA rose 33.94% year-over-year to -$22.3 million; the trailing twelve-month figure through Mar 2026 stood at -$97.8 million (up 15.91% YoY), and the FY2025 full-year result was -$109.3 million, down 3.3% from the prior year.
  • EBITDA climbed to -$22.3 million in Q1 2026, from -$23.1 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$14.0 million in Q2 2023 to a low of -$33.8 million in Q1 2025.
  • A 5-year average of -$22.6 million and a median of -$22.3 million in 2026 frame the typical range for EBITDA.
  • Across the five-year window, EBITDA slumped 82.86% in 2024 and soared 33.94% in 2026, its largest moves.
  • Tracing LXEO's EBITDA over 5 years: stood at -$15.2 million in 2022, then rose by 1.47% to -$15.0 million in 2023, then tumbled by 82.86% to -$27.4 million in 2024, then increased by 15.58% to -$23.1 million in 2025, then climbed by 3.39% to -$22.3 million in 2026.
  • Business Quant data shows LXEO's EBITDA at -$22.3 million in Q1 2026, -$23.1 million in Q4 2025, and -$21.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Lexeo Therapeutics 379.94 Mn 379.94 Mn - -22.33 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -22.33 Mn
Dec 31, 2025 -23.12 Mn
Sep 30, 2025 -21.65 Mn
Jun 30, 2025 -30.69 Mn
Mar 31, 2025 -33.81 Mn
Dec 31, 2024 -27.38 Mn
Sep 30, 2024 -31.54 Mn
Jun 30, 2024 -23.55 Mn
Mar 31, 2024 -23.29 Mn
Dec 31, 2023 -14.97 Mn
Sep 30, 2023 -20.27 Mn
Jun 30, 2023 -13.98 Mn
Mar 31, 2023 -19.29 Mn
Dec 31, 2022 -15.20 Mn
Sep 30, 2022 -17.48 Mn