Growth Metrics

LeonaBio (LONA) Operating Income (2019 - 2026)

LeonaBio (LONA) reported Operating Income of -$17.2 million for Q1 2026, down 80.52% year-over-year from -$88.3 million in Q1 2025, and up 78.09% on a QoQ basis from -$78.6 million in Q4 2025.

LeonaBio (LONA) has 8 years of Operating Income data on file, last reported at -$17.2 million in Q1 2026.

  • Quarterly Operating Income fell 80.52% year-over-year to -$17.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$109.9 million (down 32.86% YoY) and the FY2025 annual result came in at -$102.3 million, down 1.35% from the prior year.
  • Operating Income advanced to -$17.2 million in Q1 2026 per LONA's latest filing, from -$78.6 million in the prior quarter.
  • Across five years, Operating Income topped out at -$6.9 million in Q3 2025 and bottomed at -$78.6 million in Q4 2025.
  • The 5-year median for Operating Income is -$27.7 million (2024), against an average of -$26.5 million.
  • Peak annual rise in Operating Income reached 76.79% in 2025, while the deepest fall reached 404.72% in 2025.
  • Tracing LONA's Operating Income over 5 years: stood at -$32.9 million in 2022, then advanced by 11.88% to -$29.0 million in 2023, then jumped by 46.35% to -$15.6 million in 2024, then plunged by 404.72% to -$78.6 million in 2025, then jumped by 78.09% to -$17.2 million in 2026.
  • Per Business Quant, the three latest LONA Operating Income figures stand at -$17.2 million (Q1 2026), -$78.6 million (Q4 2025), and -$6.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.97 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 268.64 Mn
10 LeonaBio 181.52 Mn 113.84 Mn - -17.21 Mn

Historic Data

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DateValue
Mar 31, 2026 -17.21 Mn
Dec 31, 2025 -78.57 Mn
Sep 30, 2025 -6.87 Mn
Jun 30, 2025 -7.29 Mn
Mar 31, 2025 -9.54 Mn
Dec 31, 2024 -15.57 Mn
Sep 30, 2024 -29.62 Mn
Jun 30, 2024 -28.03 Mn
Mar 31, 2024 -27.69 Mn
Dec 31, 2023 -29.01 Mn
Sep 30, 2023 -35.04 Mn
Jun 30, 2023 -31.64 Mn
Mar 31, 2023 -29.77 Mn
Dec 31, 2022 -32.93 Mn
Sep 30, 2022 -24.13 Mn
Jun 30, 2022 -23.57 Mn
Mar 31, 2022 -23.39 Mn
Dec 31, 2021 -18.78 Mn
Sep 30, 2021 -17.83 Mn
Jun 30, 2021 -16.64 Mn
Mar 31, 2021 -10.78 Mn
Dec 31, 2020 -9.08 Mn
Sep 30, 2020 -7.40 Mn
Jun 30, 2020 -2.25 Mn
Mar 31, 2020 -1.27 Mn
Dec 31, 2019 -1.12 Mn
Sep 30, 2019 -1.54 Mn