LeonaBio (LONA) Operating Income (2019 - 2026)

LeonaBio (LONA) reported Operating Income of -$17.2 million for Q1 2026, down 80.52% year-over-year from -$88.3 million in Q1 2025, and up 78.09% quarter-over-quarter from -$78.6 million in Q4 2025.

LeonaBio (LONA) Operating Income (2019 - 2026) Analysis & Trends

LeonaBio (LONA) has 8 years of Operating Income data on file, last reported at -$17.2 million in Q1 2026.

  • Operating Income for Q1 2026 came in at -$17.2 million, down 80.52% year-over-year; the trailing twelve-month figure through Mar 2026 was -$109.9 million (down 32.86% YoY), and the FY2025 annual result was -$102.3 million, down 1.35% from the prior year.
  • Operating Income grew to -$17.2 million in Q1 2026 per LONA's latest filing, from -$78.6 million in the prior quarter.
  • Over five years, Operating Income peaked at -$6.9 million in Q3 2025 and troughed at -$78.6 million in Q4 2025.
  • A 5-year average of -$26.5 million and a median of -$27.7 million in 2024 frame the typical range for Operating Income.
  • On a YoY basis, Operating Income climbed as much as 76.79% in 2025 and fell as far as 404.72% in 2025.
  • A 5-year view of Operating Income shows it stood at -$32.9 million in 2022, then grew by 11.88% to -$29.0 million in 2023, then soared by 46.35% to -$15.6 million in 2024, then slumped by 404.72% to -$78.6 million in 2025, then soared by 78.09% to -$17.2 million in 2026.
  • Business Quant data shows LONA's Operating Income at -$17.2 million in Q1 2026, -$78.6 million in Q4 2025, and -$6.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 LeonaBio 154.12 Mn 86.44 Mn - -17.21 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -17.21 Mn
Dec 31, 2025 -78.57 Mn
Sep 30, 2025 -6.87 Mn
Jun 30, 2025 -7.29 Mn
Mar 31, 2025 -9.54 Mn
Dec 31, 2024 -15.57 Mn
Sep 30, 2024 -29.62 Mn
Jun 30, 2024 -28.03 Mn
Mar 31, 2024 -27.69 Mn
Dec 31, 2023 -29.01 Mn
Sep 30, 2023 -35.04 Mn
Jun 30, 2023 -31.64 Mn
Mar 31, 2023 -29.77 Mn
Dec 31, 2022 -32.93 Mn
Sep 30, 2022 -24.13 Mn
Jun 30, 2022 -23.57 Mn
Mar 31, 2022 -23.39 Mn
Dec 31, 2021 -18.78 Mn
Sep 30, 2021 -17.83 Mn
Jun 30, 2021 -16.64 Mn