LeonaBio (LONA) EBITDA (2019 - 2026)

LeonaBio (LONA) reported EBITDA of -$33.0 million for Q1 2026, down 260.26% year-over-year from $20.6 million in Q1 2025, and up 60.24% quarter-over-quarter from -$82.9 million in Q4 2025.

LeonaBio (LONA) EBITDA (2019 - 2026) Analysis & Trends

LeonaBio (LONA) has 8 years of EBITDA data on file, last reported at -$33.0 million in Q1 2026.

  • EBITDA for Q1 2026 came in at -$33.0 million, down 260.26% year-over-year; the trailing twelve-month figure through Mar 2026 was -$129.4 million (down 62.57% YoY), and the FY2025 annual result was -$105.6 million, down 9.34% from the prior year.
  • EBITDA improved to -$33.0 million in Q1 2026 per LONA's latest filing, from -$82.9 million in the prior quarter.
  • Over five years, EBITDA peaked at -$6.6 million in Q3 2025 and troughed at -$82.9 million in Q4 2025.
  • A 5-year average of -$26.4 million and a median of -$26.8 million in 2024 frame the typical range for EBITDA.
  • On a YoY basis, EBITDA climbed as much as 76.97% in 2025 and fell as far as 452.42% in 2025.
  • A 5-year view of EBITDA shows it stood at -$29.6 million in 2022, then grew by 8.99% to -$27.0 million in 2023, then jumped by 44.34% to -$15.0 million in 2024, then sank by 452.42% to -$82.9 million in 2025, then jumped by 60.24% to -$33.0 million in 2026.
  • Business Quant data shows LONA's EBITDA at -$33.0 million in Q1 2026, -$82.9 million in Q4 2025, and -$6.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 LeonaBio 154.12 Mn 86.44 Mn - -32.96 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -32.96 Mn
Dec 31, 2025 -82.89 Mn
Sep 30, 2025 -6.61 Mn
Jun 30, 2025 -6.97 Mn
Mar 31, 2025 -9.15 Mn
Dec 31, 2024 -15.01 Mn
Sep 30, 2024 -28.70 Mn
Jun 30, 2024 -26.76 Mn
Mar 31, 2024 -26.13 Mn
Dec 31, 2023 -26.96 Mn
Sep 30, 2023 -32.71 Mn
Jun 30, 2023 -29.51 Mn
Mar 31, 2023 -26.89 Mn
Dec 31, 2022 -29.62 Mn
Sep 30, 2022 -20.74 Mn
Jun 30, 2022 -24.80 Mn
Mar 31, 2022 -22.05 Mn
Dec 31, 2021 -16.73 Mn
Sep 30, 2021 -15.71 Mn
Jun 30, 2021 -13.97 Mn