Growth Metrics

LeonaBio (LONA) EBITDA (2019 - 2026)

LeonaBio (LONA) reported EBITDA of -$33.0 million for Q1 2026, down 260.26% year-over-year from $20.6 million in Q1 2025, and up 60.24% on a QoQ basis from -$82.9 million in Q4 2025.

LeonaBio (LONA) has 8 years of EBITDA data on file, last reported at -$33.0 million in Q1 2026.

  • Quarterly EBITDA fell 260.26% year-over-year to -$33.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$129.4 million (down 62.57% YoY) and the FY2025 annual result came in at -$105.6 million, down 9.34% from the prior year.
  • EBITDA rose to -$33.0 million in Q1 2026 per LONA's latest filing, from -$82.9 million in the prior quarter.
  • Across five years, EBITDA topped out at -$6.6 million in Q3 2025 and bottomed at -$82.9 million in Q4 2025.
  • The 5-year median for EBITDA is -$26.8 million (2024), against an average of -$26.4 million.
  • Peak annual rise in EBITDA reached 76.97% in 2025, while the deepest fall reached 452.42% in 2025.
  • Tracing LONA's EBITDA over 5 years: stood at -$29.6 million in 2022, then advanced by 8.99% to -$27.0 million in 2023, then surged by 44.34% to -$15.0 million in 2024, then tumbled by 452.42% to -$82.9 million in 2025, then surged by 60.24% to -$33.0 million in 2026.
  • Per Business Quant, the three latest LONA EBITDA figures stand at -$33.0 million (Q1 2026), -$82.9 million (Q4 2025), and -$6.6 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 LeonaBio 181.52 Mn 113.84 Mn - -32.96 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -32.96 Mn
Dec 31, 2025 -82.89 Mn
Sep 30, 2025 -6.61 Mn
Jun 30, 2025 -6.97 Mn
Mar 31, 2025 -9.15 Mn
Dec 31, 2024 -15.01 Mn
Sep 30, 2024 -28.70 Mn
Jun 30, 2024 -26.76 Mn
Mar 31, 2024 -26.13 Mn
Dec 31, 2023 -26.96 Mn
Sep 30, 2023 -32.71 Mn
Jun 30, 2023 -29.51 Mn
Mar 31, 2023 -26.89 Mn
Dec 31, 2022 -29.62 Mn
Sep 30, 2022 -20.74 Mn
Jun 30, 2022 -24.80 Mn
Mar 31, 2022 -22.05 Mn
Dec 31, 2021 -16.73 Mn
Sep 30, 2021 -15.71 Mn
Jun 30, 2021 -13.97 Mn
Mar 31, 2021 -8.87 Mn
Dec 31, 2020 -7.68 Mn
Sep 30, 2020 -8.45 Mn
Jun 30, 2020 -1.99 Mn
Mar 31, 2020 -1.81 Mn
Dec 31, 2019 -974,000.00
Sep 30, 2019 -1.53 Mn