LENZ Therapeutics (LENZ) Return on Equity [ROE] (2021 - 2026)
LENZ Therapeutics (LENZ) recorded Return on Equity [ROE] of -54.11% in Q2 2026, down 27.81 percentage points from -26.30% a year earlier and down 13.04 percentage points from the prior quarter.
LENZ Therapeutics (LENZ) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, LENZ Therapeutics reported Return on Equity [ROE] of -33.63%, up 55.74 percentage points from FY2024.
- Annual Return on Equity [ROE] has a four-year change of +10.78 percentage points (FY2021 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -89.37% in FY2024, -56.74% in FY2022 (-12.33 pp) and -44.41% in FY2021.
- The Q2 2026 figure is the lowest quarterly Return on Equity [ROE] since Q1 2024.
- On a year-over-year basis, Return on Equity [ROE] has declined for four consecutive quarters, with an average year-over-year change of +24.69 percentage points over the last six quarters.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 195.04 percentage points in Q1 2025, against a drop of 51.82 percentage points in Q4 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -41.07% (Q1 2026), -34.34% (Q4 2025) and -29.41% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | LENZ Therapeutics | 120.64 Mn | 120.64 Mn | 5.21 Mn | -54.11% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -54.11% |
| Mar 31, 2026 | -41.07% |
| Dec 31, 2025 | -34.34% |
| Sep 30, 2025 | -29.41% |
| Jun 30, 2025 | -26.30% |
| Mar 31, 2025 | -24.10% |
| Dec 31, 2024 | -23.09% |
| Sep 30, 2024 | -28.71% |
| Jun 30, 2024 | -36.15% |
| Mar 31, 2024 | -219.14% |
| Dec 31, 2022 | -69.86% |
| Sep 30, 2022 | -29.62% |
| Jun 30, 2022 | -24.67% |
| Mar 31, 2022 | -20.71% |
| Dec 31, 2021 | -18.05% |
| Sep 30, 2021 | -29.61% |
| Jun 30, 2021 | -70.59% |
LENZ Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=LENZ&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "LENZ", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=LENZ&period=max&api_key=YOUR_API_KEY");
const data = await res.json();