LENZ Therapeutics (LENZ) Operating Income (2020 - 2026)

LENZ Therapeutics (LENZ) reported Operating Income of -$44.1 million for Q1 2026, down 160.68% year-over-year from $72.7 million in Q1 2025, and down 14.75% on a QoQ basis from -$38.5 million in Q4 2025.

LENZ Therapeutics (LENZ) has 7 years of Operating Income data on file, last reported at -$44.1 million in Q1 2026.

  • Quarterly Operating Income fell 160.68% year-over-year to -$44.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$118.3 million (down 99.05% YoY) and the FY2025 annual result came in at -$91.1 million, down 55.5% from the prior year.
  • Operating Income slipped to -$44.1 million in Q1 2026 per LENZ's latest filing, from -$38.5 million in the prior quarter.
  • Across five years, Operating Income topped out at -$12.6 million in Q1 2023 and bottomed at -$44.1 million in Q1 2026.
  • The 5-year median for Operating Income is -$18.9 million (2025), against an average of -$21.9 million.
  • The widest annual swing landed in 2022, when Operating Income slumped 177.09%; it then soared 51.4% in 2023.
  • Tracing LENZ's Operating Income over 5 years: stood at -$26.8 million in 2022, then increased by 6.59% to -$25.0 million in 2023, then soared by 39.07% to -$15.2 million in 2024, then plunged by 152.63% to -$38.5 million in 2025, then declined by 14.75% to -$44.1 million in 2026.
  • Per Business Quant, the three latest LENZ Operating Income figures stand at -$44.1 million (Q1 2026), -$38.5 million (Q4 2025), and -$18.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 LENZ Therapeutics 235.77 Mn 235.77 Mn 825,000.00 -44.14 Mn

Historic Data

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DateValue
Mar 31, 2026 -44.14 Mn
Dec 31, 2025 -38.46 Mn
Sep 30, 2025 -18.89 Mn
Jun 30, 2025 -16.86 Mn
Mar 31, 2025 -16.93 Mn
Dec 31, 2024 -15.23 Mn
Sep 30, 2024 -12.95 Mn
Jun 30, 2024 -14.35 Mn
Mar 31, 2024 -16.09 Mn
Dec 31, 2023 -24.99 Mn
Sep 30, 2023 -19.87 Mn
Jun 30, 2023 -14.96 Mn
Mar 31, 2023 -12.62 Mn
Dec 31, 2022 -26.75 Mn
Sep 30, 2022 -26.15 Mn
Jun 30, 2022 -26.78 Mn
Mar 31, 2022 -25.96 Mn
Dec 31, 2021 -18.94 Mn
Sep 30, 2021 -14.60 Mn
Jun 30, 2021 -17.53 Mn
Mar 31, 2021 -9.37 Mn
Dec 31, 2020 -8.32 Mn
Sep 30, 2020 -3.76 Mn
Jun 30, 2020 -1.29 Mn