Growth Metrics

Legend Biotech (LEGN) Operating Income (2019 - 2025)

Legend Biotech (LEGN) posted Operating Income of -$19.7 million for Q4 2025, up 54.66% on a QoQ basis from -$43.5 million in Q3 2025, and up 75.16% year-over-year from -$11.2 million in Q4 2024.

Legend Biotech (LEGN) has 7 years of Operating Income data on file, last reported at -$19.7 million in Q4 2025.

  • In Q4 2025, Operating Income rose 75.16% year-over-year to -$19.7 million; the TTM figure through Dec 2025 stood at $562.2 million (up 57.29% YoY), while the FY2025 annual figure was -$136.5 million, up 55.9% from the prior year.
  • Operating Income grew to -$19.7 million in Q4 2025, from -$43.5 million in the prior quarter.
  • Across five years, Operating Income topped out at $79.5 billion in Q4 2023 and bottomed at -$13.4 billion in Q1 2021.
  • A 5-year average of $3.4 billion and a median of $116.1 million in 2022 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2021 — Operating Income sank 23850.29% — and 2023, when it jumped 72638.02%.
  • Year by year, Operating Income stood at $89.8 million in 2021, then advanced by 21.62% to $109.2 million in 2022, then jumped by 72638.02% to $79.5 billion in 2023, then sank by 100.1% to -$79.3 million in 2024, then jumped by 75.16% to -$19.7 million in 2025.
  • The last three Operating Income figures came in at -$19.7 million (Q4 2025), -$43.5 million (Q3 2025), and $337.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 Revolution Medicines 32.39 Bn 32.39 Bn - -445.22 Mn

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -19.70 Mn
Sep 30, 2025 -43.45 Mn
Jun 30, 2025 337.90 Mn
Mar 31, 2025 287.47 Mn
Dec 31, 2024 -79.30 Mn
Sep 30, 2024 -70.36 Mn
Jun 30, 2024 304.44 Mn
Mar 31, 2024 202.66 Mn
Dec 31, 2023 79.46 Bn
Sep 30, 2023 198.87 Mn
Jun 30, 2023 175.45 Mn
Mar 31, 2023 125.48 Mn
Dec 31, 2022 109.25 Mn
Sep 30, 2022 136.27 Mn
Jun 30, 2022 71.41 Mn
Mar 31, 2022 122.94 Mn
Dec 31, 2021 89.83 Mn
Sep 30, 2021 81.47 Mn
Jun 30, 2021 96.16 Mn
Mar 31, 2021 -13.40 Bn
Dec 31, 2020 92.71 Mn
Sep 30, 2020 72.15 Mn
Jun 30, 2020 60.12 Mn
Mar 31, 2020 56.43 Mn
Dec 31, 2019 74.22 Mn
Sep 30, 2019 57.12 Mn
Jun 30, 2019 39.30 Mn