Legend Biotech (LEGN) Operating Income (2019 - 2025)
Legend Biotech (LEGN) posted Operating Income of -$19.7 million for Q4 2025, up 54.66% on a QoQ basis from -$43.5 million in Q3 2025, and up 75.16% year-over-year from -$11.2 million in Q4 2024.
Legend Biotech (LEGN) has 7 years of Operating Income data on file, last reported at -$19.7 million in Q4 2025.
- In Q4 2025, Operating Income rose 75.16% year-over-year to -$19.7 million; the TTM figure through Dec 2025 stood at $562.2 million (up 57.29% YoY), while the FY2025 annual figure was -$136.5 million, up 55.9% from the prior year.
- Operating Income grew to -$19.7 million in Q4 2025, from -$43.5 million in the prior quarter.
- Across five years, Operating Income topped out at $79.5 billion in Q4 2023 and bottomed at -$13.4 billion in Q1 2021.
- A 5-year average of $3.4 billion and a median of $116.1 million in 2022 frame the typical range for Operating Income.
- Annual changes were most pronounced in 2021 — Operating Income sank 23850.29% — and 2023, when it jumped 72638.02%.
- Year by year, Operating Income stood at $89.8 million in 2021, then advanced by 21.62% to $109.2 million in 2022, then jumped by 72638.02% to $79.5 billion in 2023, then sank by 100.1% to -$79.3 million in 2024, then jumped by 75.16% to -$19.7 million in 2025.
- The last three Operating Income figures came in at -$19.7 million (Q4 2025), -$43.5 million (Q3 2025), and $337.9 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -2.97 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -19.70 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -15.76 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.14 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | -3.82 Mn |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 642.90 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 268.64 Mn |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | -445.22 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -19.70 Mn |
| Sep 30, 2025 | -43.45 Mn |
| Jun 30, 2025 | 337.90 Mn |
| Mar 31, 2025 | 287.47 Mn |
| Dec 31, 2024 | -79.30 Mn |
| Sep 30, 2024 | -70.36 Mn |
| Jun 30, 2024 | 304.44 Mn |
| Mar 31, 2024 | 202.66 Mn |
| Dec 31, 2023 | 79.46 Bn |
| Sep 30, 2023 | 198.87 Mn |
| Jun 30, 2023 | 175.45 Mn |
| Mar 31, 2023 | 125.48 Mn |
| Dec 31, 2022 | 109.25 Mn |
| Sep 30, 2022 | 136.27 Mn |
| Jun 30, 2022 | 71.41 Mn |
| Mar 31, 2022 | 122.94 Mn |
| Dec 31, 2021 | 89.83 Mn |
| Sep 30, 2021 | 81.47 Mn |
| Jun 30, 2021 | 96.16 Mn |
| Mar 31, 2021 | -13.40 Bn |
| Dec 31, 2020 | 92.71 Mn |
| Sep 30, 2020 | 72.15 Mn |
| Jun 30, 2020 | 60.12 Mn |
| Mar 31, 2020 | 56.43 Mn |
| Dec 31, 2019 | 74.22 Mn |
| Sep 30, 2019 | 57.12 Mn |
| Jun 30, 2019 | 39.30 Mn |