Legend Biotech (LEGN) Operating Income (2019 - 2025)

Legend Biotech (LEGN) reported Operating Income of -$19.7 million for Q4 2025, up 75.16% on a YoY basis from -$11.2 million in Q4 2024, and up 54.66% quarter-over-quarter from -$43.5 million in Q3 2025.

Legend Biotech (LEGN) Operating Income (2019 - 2025) Analysis & Trends

Legend Biotech has reported Operating Income for 7 years, with the latest figure at -$19.7 million in Q4 2025.

  • For the quarter ending Q4 2025, Operating Income rose 75.16% year-over-year to -$19.7 million; the trailing twelve-month figure through Dec 2025 stood at $562.2 million (up 57.29% YoY), and the FY2025 full-year result was -$136.5 million, up 55.9% from the prior year.
  • Operating Income for Q4 2025 stood at -$19.7 million, up from -$43.5 million in the prior quarter.
  • The five-year high for Operating Income was $79.5 billion in Q4 2023, with the low at -$13.4 billion in Q1 2021.
  • Historically, Operating Income has averaged $3.4 billion across 5 years, with a median of $116.1 million in 2022.
  • Annual changes were most pronounced in 2021 — Operating Income sank 23850.29% — and 2023, when it soared 72638.02%.
  • Legend Biotech's Operating Income stood at $89.8 million in 2021, then gained by 21.62% to $109.2 million in 2022, then soared by 72638.02% to $79.5 billion in 2023, then slumped by 100.1% to -$79.3 million in 2024, then soared by 75.16% to -$19.7 million in 2025.
  • The last three Operating Income figures came in at -$19.7 million (Q4 2025), -$43.5 million (Q3 2025), and $337.9 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Regeneron Pharmaceuticals 63.43 Bn 54.67 Bn 3.31 Bn 642.90 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -19.70 Mn
Sep 30, 2025 -43.45 Mn
Jun 30, 2025 337.90 Mn
Mar 31, 2025 287.47 Mn
Dec 31, 2024 -79.30 Mn
Sep 30, 2024 -70.36 Mn
Jun 30, 2024 304.44 Mn
Mar 31, 2024 202.66 Mn
Dec 31, 2023 79.46 Bn
Sep 30, 2023 198.87 Mn
Jun 30, 2023 175.45 Mn
Mar 31, 2023 125.48 Mn
Dec 31, 2022 109.25 Mn
Sep 30, 2022 136.27 Mn
Jun 30, 2022 71.41 Mn
Mar 31, 2022 122.94 Mn
Dec 31, 2021 89.83 Mn
Sep 30, 2021 81.47 Mn
Jun 30, 2021 96.16 Mn
Mar 31, 2021 -13.40 Bn