Growth Metrics

Legend Biotech (LEGN) Gross Profit (2019 - 2025)

Legend Biotech (LEGN) posted Gross Profit of $242.1 million for Q4 2025, up 10.18% on a QoQ basis from $219.7 million in Q3 2025, and up 75.94% year-over-year from $137.6 million in Q4 2024.

Legend Biotech (LEGN) has 7 years of Gross Profit data on file, last reported at $242.1 million in Q4 2025.

  • In Q4 2025, Gross Profit rose 75.94% year-over-year to $242.1 million; the TTM figure through Dec 2025 stood at $822.9 million (up 71.52% YoY), while the FY2025 annual figure was $823.1 million, up 71.55% from the prior year.
  • Gross Profit advanced to $242.1 million in Q4 2025, from $219.7 million in the prior quarter.
  • Across five years, Gross Profit topped out at $79.5 billion in Q4 2023 and bottomed at -$13.4 billion in Q1 2021.
  • A 5-year average of $3.4 billion and a median of $60.8 million in 2023 frame the typical range for Gross Profit.
  • Annual changes were most pronounced in 2021 — Gross Profit slumped 268112.76% — and 2023, when it jumped 4390174.38%.
  • Year by year, Gross Profit stood at -$13.8 million in 2021, then jumped by 113.1% to $1.8 million in 2022, then jumped by 4390174.38% to $79.5 billion in 2023, then slumped by 99.83% to $137.6 million in 2024, then surged by 75.94% to $242.1 million in 2025.
  • The last three Gross Profit figures came in at $242.1 million (Q4 2025), $219.7 million (Q3 2025), and $207.0 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn
10 Revolution Medicines 32.39 Bn 32.39 Bn -

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 242.10 Mn
Dec 31, 2025 242.10 Mn
Sep 30, 2025 219.72 Mn
Sep 30, 2025 219.72 Mn
Jun 30, 2025 207.01 Mn
Jun 30, 2025 207.01 Mn
Mar 31, 2025 154.08 Mn
Mar 31, 2025 154.08 Mn
Dec 31, 2024 137.60 Mn
Dec 31, 2024 137.60 Mn
Sep 30, 2024 115.94 Mn
Sep 30, 2024 115.94 Mn
Jun 30, 2024 156.46 Mn
Jun 30, 2024 156.46 Mn
Mar 31, 2024 69.77 Mn
Mar 31, 2024 69.77 Mn
Dec 31, 2023 79.46 Bn
Dec 31, 2023 79.46 Bn
Sep 30, 2023 74.92 Mn
Sep 30, 2023 74.92 Mn
Jun 30, 2023 51.90 Mn
Jun 30, 2023 51.90 Mn
Mar 31, 2023 18.38 Mn
Mar 31, 2023 18.38 Mn
Dec 31, 2022 1.81 Mn
Dec 31, 2022 1.81 Mn
Sep 30, 2022 8.51 Mn
Sep 30, 2022 8.51 Mn
Jun 30, 2022 -15.47 Mn
Jun 30, 2022 -15.47 Mn
Mar 31, 2022 28.74 Mn
Mar 31, 2022 28.74 Mn
Dec 31, 2021 -13.82 Mn
Dec 31, 2021 -13.82 Mn
Sep 30, 2021 -2.65 Mn
Sep 30, 2021 -2.65 Mn
Jun 30, 2021 3.45 Mn
Jun 30, 2021 3.45 Mn
Mar 31, 2021 -13.40 Bn
Mar 31, 2021 -13.40 Bn
Dec 31, 2020 16.60 Mn
Dec 31, 2020 16.60 Mn
Sep 30, 2020 2.46 Mn
Sep 30, 2020 2.46 Mn
Jun 30, 2020 2.04 Mn
Jun 30, 2020 2.04 Mn
Mar 31, 2020 5.00 Mn
Mar 31, 2020 5.00 Mn
Dec 31, 2019 6.08 Mn
Dec 31, 2019 6.08 Mn
Sep 30, 2019 13.21 Mn
Sep 30, 2019 13.21 Mn
Jun 30, 2019 5.06 Mn
Jun 30, 2019 5.06 Mn