Janux Therapeutics (JANX) Operating Income (2020 - 2026)

Janux Therapeutics (JANX) posted quarterly Operating Income of -$34.2 million for Q1 2026, up 1.96% year-over-year from -$33.6 million in Q1 2025, and up 19.31% quarter-over-quarter from -$42.4 million in Q4 2025.

Janux Therapeutics (JANX) Operating Income (2020 - 2026) Analysis & Trends

Janux Therapeutics (JANX) has reported Operating Income for 7 consecutive years, with -$34.2 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Income rose 1.96% year-over-year to -$34.2 million; the TTM figure through Mar 2026 stood at -$157.0 million (down 38.21% YoY), while the FY2025 annual figure was -$157.7 million, down 59.51% from the prior year.
  • Operating Income improved to -$34.2 million in Q1 2026 per JANX's latest filing, from -$42.4 million in the prior quarter.
  • Across five years, Operating Income topped out at -$13.5 million in Q1 2022 and bottomed at -$45.1 million in Q2 2025.
  • Historically, Operating Income has averaged -$25.3 million across 5 years, with a median of -$20.3 million in 2023.
  • Annual changes were most pronounced in 2022 — Operating Income tumbled 492.91% — and 2024, when it jumped 33.38%.
  • Janux Therapeutics' Operating Income stood at -$18.3 million in 2022, then gained by 11.66% to -$16.1 million in 2023, then slumped by 79.85% to -$29.0 million in 2024, then sank by 46.1% to -$42.4 million in 2025, then increased by 19.31% to -$34.2 million in 2026.
  • Business Quant data shows JANX's Operating Income at -$34.2 million in Q1 2026, -$42.4 million in Q4 2025, and -$35.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 Janux Therapeutics 984.58 Mn 984.58 Mn - -31.69 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -31.69 Mn
Mar 31, 2026 -34.21 Mn
Dec 31, 2025 -42.40 Mn
Sep 30, 2025 -35.25 Mn
Jun 30, 2025 -45.12 Mn
Mar 31, 2025 -34.90 Mn
Dec 31, 2024 -29.02 Mn
Sep 30, 2024 -35.84 Mn
Jun 30, 2024 -13.82 Mn
Mar 31, 2024 -20.16 Mn
Dec 31, 2023 -16.14 Mn
Sep 30, 2023 -15.81 Mn
Jun 30, 2023 -20.75 Mn
Mar 31, 2023 -20.28 Mn
Dec 31, 2022 -18.27 Mn
Sep 30, 2022 -18.02 Mn
Jun 30, 2022 -17.26 Mn
Mar 31, 2022 -13.54 Mn
Dec 31, 2021 -13.49 Mn
Sep 30, 2021 -10.90 Mn