Janux Therapeutics (JANX) EBITDA (2020 - 2026)

Janux Therapeutics (JANX) reported EBITDA of -$28.1 million for Q1 2026, down 28.23% year-over-year from -$39.2 million in Q1 2025, and up 12.71% on a QoQ basis from -$32.2 million in Q4 2025.

Janux Therapeutics (JANX) has 7 years of EBITDA data on file, last reported at -$28.1 million in Q1 2026.

  • Quarterly EBITDA fell 28.23% year-over-year to -$28.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$117.7 million (down 60.16% YoY) and the FY2025 annual result came in at -$111.5 million, down 65.15% from the prior year.
  • EBITDA advanced to -$28.1 million in Q1 2026 per JANX's latest filing, from -$32.2 million in the prior quarter.
  • Across five years, EBITDA topped out at -$7.1 million in Q2 2024 and bottomed at -$33.9 million in Q2 2025.
  • The 5-year median for EBITDA is -$17.2 million (2022), against an average of -$19.3 million.
  • The widest annual swing landed in 2022, when EBITDA tumbled 555.74%; it then soared 60.45% in 2024.
  • Tracing JANX's EBITDA over 5 years: stood at -$15.3 million in 2022, then soared by 35.27% to -$9.9 million in 2023, then plunged by 160.98% to -$25.9 million in 2024, then slipped by 24.37% to -$32.2 million in 2025, then increased by 12.71% to -$28.1 million in 2026.
  • Per Business Quant, the three latest JANX EBITDA figures stand at -$28.1 million (Q1 2026), -$32.2 million (Q4 2025), and -$23.5 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 Janux Therapeutics 914.29 Mn 914.29 Mn - -28.10 Mn

Historic Data

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DateValue
Mar 31, 2026 -28.10 Mn
Dec 31, 2025 -32.19 Mn
Sep 30, 2025 -23.50 Mn
Jun 30, 2025 -33.87 Mn
Mar 31, 2025 -21.92 Mn
Dec 31, 2024 -25.88 Mn
Sep 30, 2024 -18.61 Mn
Jun 30, 2024 -7.05 Mn
Mar 31, 2024 -15.95 Mn
Dec 31, 2023 -9.92 Mn
Sep 30, 2023 -11.68 Mn
Jun 30, 2023 -17.83 Mn
Mar 31, 2023 -16.66 Mn
Dec 31, 2022 -15.32 Mn
Sep 30, 2022 -17.07 Mn
Jun 30, 2022 -17.23 Mn
Mar 31, 2022 -14.98 Mn
Dec 31, 2021 -13.71 Mn
Sep 30, 2021 -10.76 Mn
Jun 30, 2021 -6.19 Mn
Mar 31, 2021 -2.28 Mn
Dec 31, 2020 -1.66 Mn
Sep 30, 2020 -1.26 Mn
Jun 30, 2020 -2.46 Mn