iSpecimen (ISPC) Operating Margin (2020 - 2026)
iSpecimen (ISPC) posted quarterly Operating Margin of 1627.09% for Q1 2026, down 147216.0% year-over-year from N/an in Q1 2025, and up 68.67% quarter-over-quarter from 5192.87% in Q4 2025.
iSpecimen (ISPC) Operating Margin (2020 - 2026) Analysis & Trends
iSpecimen's Operating Margin history runs 7 years deep, the most recent figure standing at 1627.09% for Q1 2026.
- In Q1 2026, Operating Margin fell 147216.0% year-over-year to 1627.09%; the TTM figure through Mar 2026 stood at 961.36% (down 82032.0% YoY), while the FY2025 annual figure was 465.42%, down 32843.0% from the prior year.
- Operating Margin for Q1 2026 stood at 1627.09%, up from 5192.87% in the prior quarter.
- The five-year high for Operating Margin was 64.07% in Q3 2024, with the low at 5192.87% in Q4 2025.
- The 5-year median for Operating Margin is 120.04% (2022), against an average of 673.23%.
- The sharpest annual moves came in 2024 and 2025: Operating Margin surged 14299 bps in 2024, then slumped 479704 bps in 2025.
- iSpecimen's Operating Margin stood at 72.31% in 2022, then sank by 54 bps to 111.49% in 2023, then plunged by 255 bps to 395.83% in 2024, then plunged by 1212 bps to 5192.87% in 2025, then jumped by 69 bps to 1627.09% in 2026.
- Business Quant data shows ISPC's Operating Margin at 1627.09% in Q1 2026, 5192.87% in Q4 2025, and 2655.19% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.88 Bn | 209.81 Bn | 8.34 Bn | 17.40% |
| 2 | Danaher | 140.65 Bn | 136.30 Bn | 3.61 Bn | 17.99% |
| 3 | Idexx Laboratories | 46.02 Bn | 45.83 Bn | 779.09 Mn | 34.98% |
| 4 | Agilent Technologies | 39.85 Bn | 38.05 Bn | 990.00 Mn | 21.74% |
| 5 | Iqvia Holdings | 39.20 Bn | 37.12 Bn | 1.44 Bn | 11.58% |
| 6 | Natera | 38.80 Bn | 37.70 Bn | 696.04 Mn | -13.42% |
| 7 | Illumina | 30.11 Bn | 28.94 Bn | 770.00 Mn | 21.14% |
| 8 | Mettler Toledo International | 28.66 Bn | 28.61 Bn | 650.22 Mn | 31.97% |
| 9 | Quest Diagnostics | 26.24 Bn | 25.61 Bn | 1.03 Bn | 15.08% |
| 10 | iSpecimen | 658,857.59 | -2.16 Mn | 71,599.00 | -1,627.09% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -1,627.09% |
| Dec 31, 2025 | -5,192.87% |
| Sep 30, 2025 | -2,655.19% |
| Jun 30, 2025 | -255.41% |
| Mar 31, 2025 | -154.93% |
| Dec 31, 2024 | -395.83% |
| Sep 30, 2024 | -64.07% |
| Jun 30, 2024 | -76.18% |
| Mar 31, 2024 | -131.03% |
| Dec 31, 2023 | -111.49% |
| Sep 30, 2023 | -78.99% |
| Jun 30, 2023 | -219.17% |
| Mar 31, 2023 | -86.18% |
| Dec 31, 2022 | -72.31% |
| Sep 30, 2022 | -120.04% |
| Jun 30, 2022 | -110.53% |
| Mar 31, 2022 | -93.64% |
| Dec 31, 2021 | -78.26% |
| Sep 30, 2021 | -53.67% |
| Jun 30, 2021 | -52.64% |