Growth Metrics

iSpecimen (ISPC) Operating Margin (2020 - 2025)

iSpecimen has reported Operating Margin over the past 6 years, most recently at 5192.87% for Q4 2025.

  • Quarterly results put Operating Margin at 5192.87% for Q4 2025, down 479704.0% from a year ago — trailing twelve months through Dec 2025 was 465.42% (down 32843.0% YoY), and the annual figure for FY2025 was 465.42%, down 32843.0%.
  • Operating Margin for Q4 2025 was 5192.87% at iSpecimen, down from 2655.19% in the prior quarter.
  • Over the last five years, Operating Margin for ISPC hit a ceiling of 31.81% in Q1 2021 and a floor of 5192.87% in Q4 2025.
  • Median Operating Margin over the past 5 years was 102.08% (2022), compared with a mean of 501.71%.
  • Biggest five-year swings in Operating Margin: surged 14299bps in 2024 and later tumbled -479704bps in 2025.
  • iSpecimen's Operating Margin stood at 78.26% in 2021, then grew by 8bps to 72.31% in 2022, then tumbled by -54bps to 111.49% in 2023, then crashed by -255bps to 395.83% in 2024, then tumbled by -1212bps to 5192.87% in 2025.
  • The last three reported values for Operating Margin were 5192.87% (Q4 2025), 2655.19% (Q3 2025), and 255.41% (Q2 2025) per Business Quant data.