International Stem Cell (ISCO) EBT (2010 - 2026)
International Stem Cell (ISCO) posted quarterly EBT of -$203000.0 for Q4 2025, down 1791.67% year-over-year from $12000.0 in Q4 2024, and up 51.78% quarter-over-quarter from -$421000.0 in Q3 2025.
International Stem Cell (ISCO) EBT (2010 - 2026) Analysis & Trends
International Stem Cell (ISCO) has reported EBT for 16 consecutive years, with -$203000.0 the latest figure, recorded in Q4 2025.
- In Q4 2025, EBT fell 1791.67% year-over-year to -$203000.0; the TTM figure through Dec 2025 stood at -$2.0 million (down 127.78% YoY), while the FY2025 annual figure was -$7.9 million, down 3.76% from the prior year.
- EBT improved to -$203000.0 in Q4 2025 per ISCO's latest filing, from -$421000.0 in the prior quarter.
- Across five years, EBT topped out at $160000.0 in Q4 2022 and bottomed at -$937000.0 in Q3 2021.
- Historically, EBT has averaged -$336900.0 across 5 years, with a median of -$294500.0 in 2023.
- Annual changes were most pronounced in 2022 — EBT jumped 145.2% — and 2023, when it tumbled 8850.0%.
- International Stem Cell's EBT stood at -$354000.0 in 2021, then surged by 145.2% to $160000.0 in 2022, then plunged by 303.12% to -$325000.0 in 2023, then jumped by 103.69% to $12000.0 in 2024, then slumped by 1791.67% to -$203000.0 in 2025.
- Business Quant data shows ISCO's EBT at -$203000.0 in Q4 2025, -$421000.0 in Q3 2025, and -$450000.0 in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 1.39 Bn |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 1.53 Bn |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 541.00 Mn |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | -767.00 Mn |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 312.46 Mn |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 177.81 Mn |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | -11.37 Mn |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 81.49 Mn |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | -264.70 Mn |
| 10 | International Stem Cell | 4.32 Mn | 3.23 Mn | 1.46 Mn | -69,000.00 |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -424,000.00 |
| Dec 31, 2025 | -203,000.00 |
| Sep 30, 2025 | -421,000.00 |
| Jun 30, 2025 | -450,000.00 |
| Mar 31, 2025 | -935,000.00 |
| Dec 31, 2024 | 12,000.00 |
| Sep 30, 2024 | -125,000.00 |
| Jun 30, 2024 | -505,000.00 |
| Mar 31, 2024 | -264,000.00 |
| Dec 31, 2023 | -325,000.00 |
| Sep 30, 2023 | -131,000.00 |
| Jun 30, 2023 | -179,000.00 |
| Mar 31, 2023 | -34,000.00 |
| Dec 31, 2022 | 160,000.00 |
| Sep 30, 2022 | -335,000.00 |
| Jun 30, 2022 | -2,000.00 |
| Mar 31, 2022 | -9,000.00 |
| Dec 31, 2021 | -354,000.00 |
| Sep 30, 2021 | -937,000.00 |
| Jun 30, 2021 | -901,000.00 |